AI Article Synopsis
- This text discusses a case of a 59-year-old woman who developed optic neuritis and brainstem encephalitis linked to her recent COVID-19 infection, highlighted by the presence of anti-MOG antibodies.
- An MRI and serological tests confirmed her condition, showing optic nerve thickening and specific antibodies related to both the virus and her neurological issues.
- The findings suggest that a history of COVID-19 can lead to autoimmune disorders like anti-MOG disease, necessitating increased awareness among medical professionals.
Article Abstract
(1) Introduction: There have been numerous reports on the neuroinvasive competence of SARS-CoV-2. Here, we present a case with anti-MOG positive bilateral optic neuritis and brainstem encephalitis secondary to COVID-19 infection. Additionally, we present a review of the current literature regarding the manifestation of anti-MOG positive optic neuritis as well as anti-MOG positive encephalitis after COVID-19 infection. (2) Case Report: A 59-year-old female patient, with a recent history of COVID-19 infection, presented a progressive reduction of visual acuity and bilateral retrobulbar pain for the last 20 days. An ophthalmological examination revealed a decreased visual acuity (counting fingers) and a bilateral papilledema. An MRI scan of the brain revealed a mild thickening of the bilateral optic nerves and high-intensity lesions in the medial and right lateral pons. A high titer of IgG and IgM antibodies against SARS-CoV-2 in serum and antibodies against myelin oligodendrocyte glycoprotein (anti-MOG) in serum and CSF were revealed. The diagnosis of anti-MOG brainstem encephalitis and optic neuritis was set. (3) Conclusions: The history of COVID-19 infection should raise awareness about these autoimmune and infection-triggered diseases, such as anti-MOG antibody disease.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9782579 | PMC |
| http://dx.doi.org/10.3390/neurolint14040078 | DOI Listing |
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