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Investigating the psychophysiological effects of NaiKan Therapy: salivary oxytocin and cortisol release.
Front Integr Neurosci
February 2025
Shanghai Sipo Polytechnic, Shanghai, China.
NaiKan Therapy, a method of self-reflection and introspection, has garnered considerable interest for its psychological benefits. However, its physiological impacts, particularly on hormonal regulation, remain underexplored. In this study, we aimed to investigate the effects of NaiKan Therapy on salivary oxytocin and cortisol release, shedding light on the psychophysiological mechanisms underlying this introspective practice.
View Article and Find Full Text PDFNeuropsychiatric complications including depression and cognitive impairment develop, persist, and worsen in the years after traumatic brain injury (TBI), negatively affecting life and lifespan. Inflammatory responses mediated by microglia are associated with the transition from acute to chronic neuroinflammation after TBI. Moreover, type I interferon (IFN-I) signaling is a key mediator of inflammation during this transition.
View Article and Find Full Text PDFExperimenters' sex modulates anxiety-like behavior, contextual fear, and microglial oxytocin transcription in mice.
Behav Brain Res
April 2025
Department of Psychiatry, Graduate School of Medicine, Tohoku University, Sendai 980-8573, Japan; Department of Disaster Psychiatry, International Research Institute for Disaster Science, Tohoku University, Sendai 980-8573, Japan.
Oxytocin (OXT) is a neuropeptide known for modulating anxiety and fear memory. We have reported that microglial cytokine regulates contextual fear memory and that microglial OXT positively correlates with cytokine secretion. However, the relationship between contextual fear memory and microglial OXT expression remains unclear.
View Article and Find Full Text PDFThe loss of a parent during childhood is a profound event with enduring impacts on psychological and emotional development. This study investigates the long-term effects of childhood parental loss on attachment patterns and openness to experience, with a focus on the epigenetic modulation of the oxytocin and dopamine systems. The sample included 371 participants (51.
View Article and Find Full Text PDFPulsed red light photobiomodulation ameliorates oxytocin-induced primary dysmenorrhea in mice by inhibiting oxidative stress and lipid accumulation.
J Photochem Photobiol B
March 2025
School of Information Science and Technology, Fudan University, Shanghai 200433, China; Zhongshan Fudan Joint Innovation Center, Zhongshan 528400, Guangdong Province, China. Electronic address:
Photobiomodulation (PBM) has gained attention as a kind of anti-pain or anti-inflammation therapy, yet its efficacy in mitigating the symptoms and underlying metabolic disturbances of primary dysmenorrhea remains underexplored. Here, 630 nm light reduced menstrual pain and prostaglandin F/prostaglandin E dysregulation, regulated oxidation and lipid peroxidation levels, and improved uterus damage in oxytocin-induced mice. Notably, pulsed wave (PW) treatment exhibited superior efficacy compared to continuous wave application.
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