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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9761327PMC
http://dx.doi.org/10.1016/j.jdcr.2022.11.004DOI Listing

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Article Synopsis
  • Chromoblastomycosis (CBM) is a chronic skin and tissue infection that has been documented in Pakistan, highlighting varied demographics and treatment outcomes.
  • A study analyzed 16 cases of CBM from 2016 to 2022, revealing that most patients were young males, predominantly affected in the lower extremities, and showing specific histopathological features.
  • The findings emphasize the need for increased awareness of CBM among healthcare providers in Pakistan, particularly for patients with relevant histories, and call for enhanced collaboration among clinicians and lab specialists for timely diagnosis and treatment.
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Chromoblastomycosis, a chronic fungal infection of skin and subcutaneous tissue arises as a result of traumatic inoculation of exposed areas of the body. We present a unique case of chromoblastomycosis caused by Exophiala janselmei in a female farmer who presented with multiple smooth non-tender nodules on trunk and limbs for 5 years and pigmented indurated plaques on her face for 2 years along with deformities of her hands. Imaging investigations revealed multiple lytic lesions in the bones of the upper and lower limbs.

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Cutaneous chromoblastomycosis is a chronic subcutaneous fungal disease of the skin caused by , especially by , ,and species affecting the skin, lungs, intestines, stomach, and central nervous system. It is treated using itraconazole in mild cases and amphotericin B in severe cases. A six-year-old female child presented to the Dermatology Outpatient Department with pigmented brown to blackish tanned plaques and verrucous lesions on the face and extremities.

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