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Precision medicine using molecular-target drugs in psoriatic arthritis.
Ther Adv Musculoskelet Dis
January 2025
The First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Japan, 1-1 Iseigaoka, Yahata-nishi, Kitakyushu 807-8555, Japan.
Psoriatic arthritis (PsA) presents various clinical manifestations, including skin lesions, peripheral arthritis, axial involvement, enthesitis, nail involvement, dactylitis, and uveitis. In addition, it causes a high incidence of lifestyle-related diseases and an increase in cerebrovascular and cardiovascular events. As the pathology of PsA has been clarified, molecular-targeted drugs targeting tumor necrosis factor-α, interleukin (IL)-17A, IL-17A/F, IL-17 receptor, IL-12/23(p40), IL-23p19, Cytotoxic T-lymphocyte Antigen-4 (CTLA-4), Janus kinase, and phosphodiesterase-4 have been developed and are widely used in clinical practice.
View Article and Find Full Text PDFSuitability, acceptability, feasibility of modern menstrual methods: a qualitative study in Coimbatore district, Tamil Nadu, India.
Front Glob Womens Health
December 2024
Department of Community Medicine, KMCH Institute of Health Sciences and Research, Coimbatore, India.
Objective: To examine women's perceptions of modern menstrual hygiene methods (MMHM), such as tampons and menstrual cups, focusing on socio-demographic variations and special groups in the Coimbatore district of Tamil Nadu.
Methods: A qualitative study among women of reproductive age (15-49 years) group was conducted using Focus Group Discussions (FGDs) among twelve women subgroups independently in 2023.
Results: The present study involved 23 focus group discussions (FGDs) across various groups of women, including those in formal and informal sectors, urban and rural areas, school and college students, healthcare workers, women in sports, tribal women, transgender women, and female sex workers (FSW), with a total of 188 participants.
Why Teens Don't Talk: Understanding the Role of Stigma Within Barriers to Help Seeking.
Focus (Am Psychiatr Publ)
January 2025
The Jed Foundation, New York, New York.
The stigma of mental illness, among a larger set of barriers to help seeking, has been understudied among teens. These barriers and the sources of support were examined through an online survey with 1,428 U.S.
View Article and Find Full Text PDFEthical Considerations Related to Stigma in Mental Health Aspects of Treating Substance Use Disorders.
Focus (Am Psychiatr Publ)
January 2025
Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York.
Stopping Mental Illness Stigma: Changing Attitudes, Language, and Policies.
Focus (Am Psychiatr Publ)
January 2025
Department of Management, University of Utah, Salt Lake City.
Stigma has been a pervasive and stubborn part of the mental illness landscape, but it need not be. This article explores the nature of mental health stigma, where it comes from, how it is manifested, how it harms people, and what can be done about it. The article articulates the need to clearly understand three major levels of mental health stigma-structural (e.
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