Aim: Skeletal involvement of is rare and normally associated with disseminated cryptococcosis or potential predisposing factors. Here, we report an atypical case of osteoarticular cryptococcosis in an immunocompetent patient.
Case Presentation: We report a case of cryptococcal osteomyelitis in a 45-year-old female who presented with swelling and pain in the left inner thigh. After a biopsy of the pubic bone and surrounding soft tissue, the pathological results and bacterial culture of the biopsy tissue confirmed infection. After draining the pus by aspiration and administering oral fluconazole (400 mg/d) treatment, the patient's symptoms disappeared.
Conclusion: is a rare etiology of infection of the entire pubis, and oral fluconazole and pus aspiration could benefit some cryptococcal osteomyelitis patients with soft-tissue cryptococcal infection.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759975 | PMC |
http://dx.doi.org/10.2147/IDR.S390881 | DOI Listing |
Heliyon
October 2024
Department of Orthopedic Surgery, The 909th Hospital, School of Medicine, Xiamen University, Zhangzhou, 363000, Fujian Province, China.
Background: is an opportunistic fungal pathogen widely distributed in nature, commonly found in soil and bird droppings such as pigeons. Cryptococcal osteomyelitis is usually found in immunocompromised patients, in an unusual condition Cryptococcus invades the bone. It usually occurs as a part of disseminated infection and is rarely isolated, and isolated cryptococcal osteomyelitis of the radius is rarer.
View Article and Find Full Text PDFInfect Drug Resist
September 2024
Department of Tuberculosis, Hangzhou Red Cross Hospital, Hangzhou, People's Republic of China.
JBJS Case Connect
July 2024
Department of Orthopaedic Surgery and Rehabilitation, The University of Texas Medical Branch, Galveston, Texas.
Case: A 38-year-old woman presented to our clinic with right knee pain and difficulty ambulating. After cultures were obtained, a cryptococcal infection of the patella was identified. Subsequent workup revealed previously undiagnosed HIV/AIDS and a disseminated cryptococcal infection.
View Article and Find Full Text PDFAm J Case Rep
July 2024
Department of Infectious Diseases, The First College of Clinical Medical Science, China Three Gorges University & Yichang Central People's Hospital, Yichang, Hubei, China.
BACKGROUND Cryptococcosis is an opportunistic fungal infection that typically occurs in patients with compromised immune systems, primarily affecting the respiratory and central nervous systems. However, cryptococcal osteomyelitis is a rare manifestation of cryptococcal infection, characterized by nonspecific clinical features. Here, we present a case of vertebral cryptococcal osteomyelitis in a middle-aged woman and discuss diagnostic approaches.
View Article and Find Full Text PDFJ Orthop Case Rep
June 2024
Department of Orthopaedic Surgery, Section of Orthopaedic Trauma and Adult Reconstruction, ProMedica Toledo Hospital, Toledo, OH.
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