Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.5578/tt.20229615 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The Milan Score Predicts Objective Gastroesophageal Reflux Disease in Patients With Type 2 Esophagogastric Junction.
Neurogastroenterol Motil
January 2025
Division of Gastroenterology, University of Pisa, Pisa, Italy.
Introduction: High-resolution manometry (HRM) allows assessment of esophagogastric junction (EGJ) disruption. While type 3 EGJ predicts definitive gastroesophageal reflux disease (GERD), type 2 EGJ is less clearly implicated in GERD pathogenesis. This study aimed to characterize physiologic findings in type 2 EGJ to determine if the HRM-based Milan Score can define GERD within type 2 EGJ.
View Article and Find Full Text PDFPractical Application of the COuGH RefluX Score for Patients With Laryngopharyngeal Symptoms: Real-World Assessment in Predicting Gastroesophageal Reflux Disease and Proton-Pump Inhibitor Response.
Am J Gastroenterol
November 2024
Department of Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation and Tzu Chi University, Hualien, Taiwan.
Introduction: The COuGH RefluX score has been validated to predict likelihood of gastroesophageal reflux disease (GERD) in patients with laryngopharyngeal symptoms (LPS) using parameters of cough, overweight, globus, hiatal hernia, regurgitation, and male sex. The aim of this study was to assess the real-world value of the COuGH RefluX score in predicting proton-pump inhibitor (PPI) response in patients with LPS.
Methods: Patients with LPS for > 3 months were prospectively enrolled and assessed using the Reflux Symptom Index and 24-hour impedance-pH monitoring.
PROsthetic MEsh Reinforcement in elective minimally invasive paraesophageal hernia repair (PROMER): an international survey.
Updates Surg
November 2024
Division of General and Foregut Surgery, Department of Biomedical Sciences for Health, IRCCS Policlinico San Donato, University of Milan, Milan, Italy.
The optimal treatment for paraesophageal hiatus hernia (PEH) is controversial. While crural buttressing with mesh shows promises in reducing recurrences, the decision to use mesh during minimally invasive PEH repair is largely subjective. Due to these uncertainties, we conducted a survey to examine current clinical practices among surgeons and to assess which are the most important determinants in the decision-making process for mesh placement.
View Article and Find Full Text PDFCollagen-V and K-α-1 Tubulin Antibodies as Potential Markers of Unsuspected GERD-Related Lung Damage: Insights from a Cross-Sectional Analysis.
Lung
December 2024
Norton Thoracic Institute, St. Joseph´s Hospital and Medical Center, Phoenix, AZ, USA.
Purpose: Our group has proposed that aspiration of gastric contents leads to exposure of normally sequestered lung self-antigens (SAgs), specifically collagen-V (Col-V) and K-α-1-tubulin (Kα1T), which elicits an immune response characterized by increasing concentrations of self-antibodies (SAbs) anti-Col-V and anti-Kα1T. We sought to establish the point prevalence of abnormally elevated concentrations of SAbs among patients with pathological gastroesophageal reflux disease (GERD) and/or hiatal hernia undergoing antireflux surgery (ARS).
Methods: For this cross-sectional study, we retrieved a plasma aliquot from the Norton Thoracic Institute BioBank from blood samples that were taken preoperatively from patients who underwent ARS between November 2019 and August 2022.
Outcomes of transoral incisionless fundoplication (TIF 2.0): a prospective multicenter cohort study in academic and community gastroenterology and surgery practices (with video).
Gastrointest Endosc
January 2025
Digestive Health Institute, University of California, Irvine, California.
Article Synopsis
- TIF 2.0 is an advanced endoscopic procedure for treating GERD, showing high clinical success (94%) and significant symptom improvement in patients after one year.
- In a study of 81 patients, most reported a dramatic increase in satisfaction from 8% to 79%, and many reduced their reliance on proton pump inhibitors from 81% to 80% post-procedure.
- The procedure demonstrated safety with no serious adverse events reported, confirming its effectiveness as an outpatient treatment for appropriate GERD patients.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!