Background: Patient-specific instrumentation (PSI) has the potential to improve the accuracy of implant positioning in total hip arthroplasty (THA). This prospective clinical study aimed to develop artificial intelligence to increase PSI production efficiency and assess accuracy, clinical outcomes, and learning curves.
Methods: A convolutional neural network was applied to automatically process computer tomography images. PSI size and position were designed to guide the acetabular preparation and femoral neck resection. Thirty patients who underwent PSI-assisted THAs were matched to thirty patients who underwent free-hand THAs, and the component positions, as well as radiographic and clinical outcomes were analyzed.
Results: PSI-assisted THA was significantly more accurate than free-hand THA at achieving the target component position. The mean absolute errors of cup inclination (P = .004) and anteversion (P < .001) were significantly smaller in the PSI group with fewer outliers. Calcar length (P = .002) and neck length (P = .026) were also more accurate in the PSI group. The leg length discrepancy was significantly lower in the PSI group (P = .002). There were no significant differences in operation time, blood loss, leg length discrepancy, or cup position among the first, second, and last 10 cases.
Conclusion: PSI-assisted THA offered more accurate component positions and better radiographic outcomes than free-hand THA. There was no evidence of a learning curve. Our findings suggest that PSI is a convenient and practical option to help surgeons achieve accurate surgical outcomes.
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http://dx.doi.org/10.1016/j.arth.2022.12.017 | DOI Listing |
Pediatr Surg Int
January 2025
Department of Paediatric Surgery, Children's Health Ireland at Crumlin, Dublin, Ireland.
Background: Appendicectomy is a common procedure in children. Regional anaesthesia helps reduce requirements for opioids and hospital stay and enhances recovery. Laparoscopic-assisted Transversus Abdominus Plane block (L-TAP) was shown to be efficient and potentially superior to port site infiltration (PSI); however, this was not previously studied in paediatric appendicitis.
View Article and Find Full Text PDFMethods Mol Biol
January 2025
AIBioMed Research Group, Taipei Medical University, Taipei, Taiwan.
SNARE proteins play a pivotal role in membrane fusion and various cellular processes. Accurate identification of SNARE proteins is crucial for elucidating their functions in both health and disease contexts. This chapter presents a novel approach employing multiscan convolutional neural networks (CNNs) combined with position-specific scoring matrix (PSSM) profiles to accurately recognize SNARE proteins.
View Article and Find Full Text PDFJ Psychiatr Res
January 2025
Department of Medicine, Universitat Internacional de Catalunya, Barcelona. c/ Dr. Josep Trueta s/n, Sant Cugat del Vallès, 08195, Barcelona, Spain. Electronic address:
Background: Determining anesthetic depth has been used to assess the optimal timing of electrical stimulus application in electroconvulsive therapy (ECT). This has improved the quality and effectiveness of seizures, as some anesthetics used can decrease efficacy. This study evaluated the influence of the Patient State Index (PSi) on the course of ECT in patients with major depressive disorder (MDD).
View Article and Find Full Text PDFHead Face Med
January 2025
Department of Oral and Maxillofacial Surgery, Heinrich Heine University Hospital Düsseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany.
Background: Virtual surgical planning for orthognathic surgery typically relies on two methods for intraoperative plan transfer: CAD/CAM occlusal splints and patient-specific implants (PSI). While CAD/CAM splints may offer limited accuracy, particularly in the vertical dimension, PSIs are constrained by higher costs and extended preparation times. Surgical navigation has emerged as a potential alternative, but existing protocols often involve invasive registration or lack transparent evaluation.
View Article and Find Full Text PDFBrain Sci
December 2024
Department of Medicine, Division of Neurology, Queen's University, Kingston, ON K7L 3N6, Canada.
Background/objectives: Cardiac arrest may cause significant hypoxic-ischemic injury leading to coma, seizures, myoclonic jerks, or status epilepticus. Mortality is high, but accurate prognostication is challenging. A multimodal approach is employed, in which electroencephalography (EEG) forms a key part with several recognised patterns of prognostic significance.
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