AI Article Synopsis
- - Two new compounds were identified from the roots of Cynanchum atratum, including a rhamnoside and a dimethoxystilbene, while five known glucosides were also isolated.
- - The structures of the new compounds were determined using various analytical techniques such as NMR and mass spectrometry.
- - Antioxidant activities were tested for all compounds using specific assays, revealing that certain glucosides showed significant antioxidant effects, suggesting their potential use as natural antioxidants.
Article Abstract
Two new rhamnosides, 18-O-α-l-rhamnopyranosylabietic acid (1) and (E)-3,5-dimethoxystilben-4'-O-α-l-rhamnopyranoside (2), five known glucosides (3-7) along with three others were isolated from Cynanchum atratum roots. The structures of new compounds were elucidated by physical data analyses such as NMR, UV, IR, HR-ESI-MS, as well as acid hydrolysis. All of them were assessed for their antioxidant activities through 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) radical ion (ABTS•), 1,1-diphenyl-2-picryl-hydrazyl radical (DPPH•) and 2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl 3-oxide radical (PTIO•) assay, with l-ascorbic acid used as the positive control. As a result, compounds 3-5 exhibited obvious antioxidant activities. These bioactive components could be promising antioxidants.
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| http://dx.doi.org/10.1016/j.carres.2022.108729 | DOI Listing |
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