AI Article Synopsis
- Oral squamous cell carcinoma (OSCC) is a prevalent type of oral cancer that necessitates early detection to enhance survival rates.
- Traditional lab-based detection methods are often slow, leading to a demand for point-of-care techniques that offer quick results.
- A modular biological sensor using transistor technology has shown effective sensitivity for detecting CIP2A protein, indicating a promising future for fast and accurate clinical diagnoses.
Article Abstract
Oral squamous cell carcinoma (OSCC) is one of the most common lip and oral cavity cancer types. It requires early detection via various medical technologies to improve the survival rate. While most detection techniques for OSCC require testing in a centralized lab to confirm cancer type, a point of care detection technique is preferred for on-site use and quick result readout. The modular biological sensor utilizing transistor-based technology has been leveraged for testing CIP2A, and optimal transistor gate voltage and load resistance for sensing setup was investigated. Sensitivities of 1 × 10 g/ml have been obtained for both detections of pure CIP2A protein and HeLa cell lysate using identical test conditions via serial dilution. The superior time-saving and high accuracy testing provides opportunities for rapid clinical diagnosis in the medical space.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750712 | PMC |
| http://dx.doi.org/10.1116/6.0002175 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!