Covid-19 revealed the strengths and weaknesses in the global education atmosphere in both developed and developing countries. To that effect, this current study explored the impacts of the covid-19 pandemic on Nigeria's education system and in the process provided a distinctive solution to the challenges facing the sustainability of education in the country. However, the closure of schools for over six months at the onset of the covid -19 pandemic, and the inability of schools to engage learners in educational activities while at home also revealed the poor state of the education system in the country, which led to the discovery of the unavailability of distance online education, web-based learning system and ICT infrastructure in the Nigerian education environment. Covid-19 incidence impacted the stability of the academic calendar, caused teachers attrition, increased the rate of students dropout, and lack of interest in digital education. These outcomes resulted in the exploration of students' and teachers' perceptions, attitudes, literacy, competency, and willingness to engage in distance online education. A cross-sectional approach was applied through an online survey to obtain data from n = 82 learners across the three levels of institutions. And SPSS was used to analyze the demography data, while SMART PLS was used for structural equation modeling (SEM). The study outcome satisfied the objectives of the study that the lack of student-teacher digital competencies influences their perception and acceptability of web-based learning approach and use of smart learning and teaching devices.
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http://dx.doi.org/10.1016/j.ijedro.2022.100219 | DOI Listing |
Int J Immunogenet
January 2025
Department of Clinical Haematology and Medical Oncology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
High degree of variability in human leukocyte antigens (HLAs) system restricts availability of histocompatible HLA-matched-related donors, thus increasing reliance on worldwide bone marrow registries network. Nevertheless, due to limited coverage/accessibility/affordability of some ethnicities in these registries, haploidentical haematopoietic stem cell transplantation (HSCT) emerged as an alternative option, though with allorecognition-mediated graft versus host disease (GvHD) (>40% cases). A dimorphism [-21 methionine (M) or threonine (T)] in HLA-B leader peptide (exon 1) which differentially influences its HLA-E binding, plausibly regulates natural killer cell functionality, affecting GvHD vulnerability and clinically in practice for donor selection.
View Article and Find Full Text PDFEur J Sport Sci
February 2025
Department of Sport and Health Sciences and Social Work, Oxford Brookes University, Oxford, UK.
Some technical limitations to using the eccentric mode to measure peak eccentric strength of the hamstrings (PTH) were raised. PTH also has limited validity to predict performance or injury risk factor. Therefore, our aim was to compare PTH and other isokinetic variables tested in the eccentric and passive modes.
View Article and Find Full Text PDFClin Anat
January 2025
Department of Neurosurgery, Tulane University School of Medicine, New Orleans, Louisiana, USA.
Recent advances in small-joint arthroscopy and cutting-edge magnetic resonance imaging systems have enabled orthopedic surgeons to perform more complex repairs of the wrist. Such repairs can include those of the triangular fibrocartilage complex (TFCC) of the wrist that necessitates a reappraisal of its morphometry with special emphasis on the relationship between its articular disc (AD) and surrounding tissues. The TFCC AD is a fibrocartilaginous, biconcave structure located between the ulnar styloid process and the carpal bones of the wrist.
View Article and Find Full Text PDFHead Neck
January 2025
Department of Pathology, All India Institute of Medical Sciences, Rishikesh, India.
Background: To correlate between immunohistochemical expression of tumor-infiltrating lymphocytes (TILs), tumor-associated macrophages (TAMs), and natural killer (NK) cells with the AJCC 8th edition TNM staging system and other disease-modifying clinico-pathological variables.
Methods: The representative histology sections of tumor invasive margin (IM) and tumor core (TC) were selected according to the International Immuno-Oncology Biomarker Working Group and were subjected to immunohistochemistry with antibodies for TILs (CD3, CD8, FOXP3), NK Cells (CD57), TAMs (CD68, CD163) and pan-leukocyte marker (CD45). Histo-immuno-density-intensity (HIDI) scoring was calculated as a product of the proportion and intensity of staining.
Chem Asian J
January 2025
IISER Bhopal Department of Chemistry, Chemistry, Indore By-pass Road, Bhauri, 462066, Bhopal, INDIA.
White-light generation using small organic molecules has gained significant attention from researchers working on the interface of supramolecular chemistry and organic materials. Self-assembled multi-chromophoric materials utilizing a drug molecule and microenvironment-sensitive intramolecular charge transfer dye as an emitter offer the possibility of tunable emission. In this investigation, we focused on white light generation via the combination of a polarity-sensitive red-emitting styryl chromone (SC) and a blue-emitting anticancer and psychotherapeutic drug Norharmane (NHM) in a self-assembled micellar system.
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