Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.gofs.2022.12.001 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The multi-omics signatures of telomere length in childhood.
BMC Genomics
January 2025
Centre for Environmental Health, Hasselt University, Hasselt, Belgium.
Background: Telomere length is an important indicator of biological age and a complex multi-factor trait. To date, the telomere interactome for comprehending the high-dimensional biological aspects linked to telomere regulation during childhood remains unexplored. Here we describe the multi-omics signatures associated with childhood telomere length.
View Article and Find Full Text PDFEpigenetic regulation of HOXA2 expression affects tumor progression and predicts breast cancer patient survival.
Cell Death Differ
January 2025
CEINGE-Biotecnologie Avanzate Franco Salvatore, Naples, Italy.
Accumulating evidence suggests that genetic and epigenetic biomarkers hold potential for enhancing the early detection and monitoring of breast cancer (BC). Epigenetic alterations of the Homeobox A2 (HOXA2) gene have recently garnered significant attention in the clinical management of various malignancies. However, the precise role of HOXA2 in breast tumorigenesis has remained elusive.
View Article and Find Full Text PDFJérôme Lejeune (1926-1994): A Pioneer in Uncovering the Connection Between Congenital Conditions and Chromosomal Anomalies.
Cureus
December 2024
Healthcare Surveillance and Bioethics, Università Cattolica del Sacro Cuore, Rome, ITA.
Jérôme Lejeune was a French physician and geneticist whose crucial contribution to the field of medicine was the discovery of an extra copy of chromosome 21 in those presenting with a range of physical and developmental anomalies known as Down syndrome. From this discovery on, the condition had a new name (trisomy 21) and a specific scientific explanation that left no room for discrimination against those affected and their parents. Lejeune promoted the idea that a medical doctor should hate the condition and love the patient: while working to find a cure for trisomy 21, Lejeune was also able to reassure his patients and their families and lead them out from under a long-standing stigma inflicted upon them.
View Article and Find Full Text PDF[Visions and repercussions of identity-release in oocyte and sperm donors: Descriptive survey among gamete donors].
Gynecol Obstet Fertil Senol
December 2024
Service d'endocrinologie, hôpital l'Archet, CHU de Nice, 151, route de Saint-Antoine de Ginestière, 06 200 Nice, France. Electronic address:
Objectives: The Bioethics Law of August 2nd, 2021 established access to origins for people conceived by gamete donation. Two years after the implementation of this disposition, what is the proportion of former gamete donors informed about access to origins, and what is their position on this matter? What could be the potential repercussions of this new law on them?
Methods: Retrospective single-center cohort study using questionnaires.
Results: When former gamete donors were asked about access to origins, only 53% of oocytes donors and 71% of sperm donors were aware of this measure.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!