Two new berkeley meroterpenoids (1 and 2), along with seven known compounds (3‒9) were isolated from a fungus, Penicillium sp. SSW03M2 GY derived from a sediment at Seosan bay, South Korea. Chemical structures of the isolated compounds were elucidated on the basis of 1D, 2D NMR, HRESIMS, and optical rotation. All the isolated compounds, 1 showed anti-virulence activity by significantly inhibiting α-toxin (Hla) secreted by methicillin-resistant Staphylococcus aureus without its growth inhibition.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1038/s41429-022-00587-7 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
F-box protein Fbx23 acts as a transcriptional coactivator to recognize and activate transcription factor Ace1.
PLoS Genet
January 2025
National Glycoengineering Research Center, Shandong University, Qingdao, China.
Protein ubiquitination is usually coupled with proteasomal degradation and is crucial in regulating protein quality. The E3 ubiquitin-protein ligase SCF (Skp1-Cullin-F-box) complex directly recognizes the target substrate via interaction between the F-box protein and the substrate. F-box protein is the determinant of substrate specificity.
View Article and Find Full Text PDFApplication of cold atmospheric plasma for decontamination of toxigenic fungi and mycotoxins: a systematic review.
Front Microbiol
January 2025
Laboratory of Food Microbiology and Mycotoxicology, Department of Food Engineering, School of Animal Science and Food Engineering, University of São Paulo, Pirassununga, Brazil.
Introduction: Microbial contamination remains a vital challenge across the food production chain, particularly due to mycotoxins-secondary metabolites produced by several genera of fungi such as , and . These toxins, including aflatoxins, fumonisins, ochratoxins, and trichothecenes (nivalenol, deoxynivalenol, T2, HT-2). These contaminants pose severe risks to human and animal health, with their potential to produce a variety of different toxic effects.
View Article and Find Full Text PDF, , and () in Brazilian caves, with the description of four new species.
Fungal Syst Evol
December 2024
Departamento de Micologia Prof. Chaves Batista, Centro de Biociências, Universidade Federal de Pernambuco (UFPE), Avenida da Engenharia, s/n, Cidade Universitária, CEP: 50740-600, Recife, PE, Brazil.
The study of the Brazilian cave mycobiota has revealed a rich but highly diverse assemblage of fungi, with , , and being the most frequently reported genera. The present study investigated the airborne fungi and fungi obtained from the bodies of bats, guano, and the soil/sediment from the caves Urubu (in the Atlantic Forest) and Furna Feia (in the Caatinga dryland forest) in the Northeast region of Brazil. Fungal strains were identified based on morphological features and multilocus phylogenetic analyses of ITS, beta-tubulin (), calmodulin (), and RNA polymerase II second largest subunit () sequences.
View Article and Find Full Text PDFFungal Planet description sheets: 1697-1780.
Fungal Syst Evol
December 2024
Westerdijk Fungal Biodiversity Institute, P.O. Box 85167, 3508 AD Utrecht, The Netherlands.
Novel species of fungi described in this study include those from various countries as follows: , from accumulated snow sediment sample. , on leaf spots of . , on submerged decaying wood in sea water, on , as endophyte from healthy leaves of .
View Article and Find Full Text PDFGlobal transcriptome changes during growth of a novel Penicillium coffeae isolate on the wheat stripe rust fungus, Puccinia striiformis f. sp. tritici.
Fungal Genet Biol
January 2025
Research School of Biology, The Australian National University, 134 Linnaeus Way, Canberra, ACT 2601, Australia. Electronic address:
Wheat stripe rust caused by the fungus Puccinia striiformis f. sp. tritici (Pst) is currently the most destructive disease of wheat.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!