T cell-eosinophil crosstalk-A new road for effective immune checkpoint blockade in breast cancer?

Cancer Cell

Department of Clinical Microbiology and Immunology, Faculty of Medicine, Tel Aviv University, Ramat Aviv, Tel Aviv, Israel. Electronic address:

Published: January 2023

Immune checkpoint blockade (ICB) has revolutionized the landscape of cancer treatment. Nevertheless, most cancer patients still do not respond to ICB. In this issue of Cancer Cell, Blomberg et al. illustrate a critical cooperation between T cells and eosinophils, which jointly enhance effectiveness of ICB in breast cancer.

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Source
http://dx.doi.org/10.1016/j.ccell.2022.11.008DOI Listing

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