AI Article Synopsis

  • Nasopharyngeal papillary adenocarcinoma (NPAC) is a rare malignant tumor originating from the nasopharyngeal epithelium, typically appearing as a papillary or polypoid mass.
  • The tumor generally affects the roof and walls of the nasopharynx, with nasal obstruction being the most common symptom, and it has a good prognosis with no reported recurrences or metastases after treatment.
  • Surgical removal is the primary treatment, though radiation therapy has been used in some cases; awareness of NPAC's subtle presentation is crucial for effective diagnosis and intervention.

Article Abstract

Nasopharyngeal papillary adenocarcinoma (NPAC) is an extremely rare primary malignant tumor. There is only a limited number of cases of NPACs reported in the literature. The neoplasm presents as an exophytic mass with a papillary or polypoid appearance derived from the nasopharyngeal surface epithelium. It can potentially involve any part of the nasopharynx, but it most commonly involves the roof, the lateral, and the posterior wall. The prognosis is very good and no recurrences or metastases have been reported. Nasal obstruction is the most common manifestation. Surgical excision is considered the most appropriate treatment method. There are also reports of patients undergoing radiation therapy. However, its role in the treatment has not been clarified. The presence of this tumor in the nasal cavity could be easily underestimated, because of its appearance. As a result, an index of suspicion is necessary for a timely diagnostic and therapeutic intervention. We present a case of NPAC in a 26-year-old female treated in our hospital.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747060PMC
http://dx.doi.org/10.7759/cureus.31444DOI Listing

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