A miniaturised structural health monitoring device has been developed capable of measuring the absolute distance between close parallel surfaces using Fabry-Pérot interferometry with nm-scale sensitivity. This is achieved by fabricating turning mirrors on two opposite cores of a multi-core fibre to produce a probe with dimensions limited only be the fibre diameter. Two fabrication processes have been investigated: Focused ion beam milling, which has resulted in a sensor measurement accuracy, sensitivity and range of ±0.056 µm, ±0.006 µm and ∼16000 µm respectively; and ultrafast laser assisted etching of the cleaved fibre end, where a sensor measurement accuracy, sensitivity and range of ±0.065 µm, ±0.006 µm and ∼7500 µm have been demonstrated.
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http://dx.doi.org/10.1364/OE.462070 | DOI Listing |
Biochemistry (Mosc)
December 2024
Faculty of Chemistry, Lomonosov Moscow State University, Moscow, 119991, Russia.
The current work presents comparative assessment of affinity of the designed DNA aptamers for extracellular domain of the human epidermal growth factor receptor (EGFR*). The affinity data of the 20 previously published aptamers are summarized. Diversity of the aptamer selection methods and techniques requires unification of the comparison algorithms, which is also necessary for designing aptamers used in the post-selection fitting to the target EGFR* protein.
View Article and Find Full Text PDFSci Rep
January 2025
Refined Imaging LLC, Baton Rouge, LA, 70810, USA.
This study describes procedures for embedding digital information into additively manufactured components as well as procedures for readout and tensile testing. Embedded digital codes were printed inside ASTM E8/E8M dumbbells using Direct Metal Laser Melting (DMLS) with an EOS M290 printer. The codes were configured as either ellipsoids or prolate spheroids in patterns given by the Cantor dust fractal.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
College of Ocean Food and Biological Engineering, Jimei University, Xiamen 361021, China. Electronic address:
Hemoglobin, composed of α- and β-chains, is essential for oxygen transport and is key in diagnosing and treating gastrointestinal and blood disorders. It also aids in detecting blood contamination and estimating transfusion volumes. Immunological methods, based on antigen-antibody interactions, are distinguished by their high sensitivity and accuracy.
View Article and Find Full Text PDFSensors (Basel)
January 2025
Beijing Key Laboratory for Precision Optoelectronic Measurement Instrument and Technology, School of Optics and Photonics, Beijing Institute of Technology, Beijing 100081, China.
Optical freeform surfaces are widely used in imaging and non-imaging systems due to their high design freedom. In freeform surface manufacturing and assembly, dynamic freeform surface measurement that can guide the next operation remains a challenge. To meet this urgent need, we propose a dynamic interferometric method based on a machine learning-configured deformable mirror (DM).
View Article and Find Full Text PDFMicromachines (Basel)
December 2024
The National Key Laboratory of Radar Detection and Sensing, Xidian University, Xi'an 710071, China.
In order to achieve high accuracy in interferometric direction-finding systems, antennas with a stable phase center in the working bandwidth are required. This article proposes a miniaturized loaded open-boundary quad-ridge horn (LOQRH) antenna with dimensions of 40 mm × 40 mm × 49 mm. First, to stabilize the phase center of the antenna, the design builds on the foundation of a quad-ridge horn antenna, where measures such as optimizing the ridge structure and introducing resistive loading were implemented to achieve size reduction.
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