Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.echo.2022.11.012 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Impact of noradrenergic inhibition on neuroinflammation and pathophysiology in mouse models of Alzheimer's disease.
J Neuroinflammation
December 2024
Department of Neurosurgery, Stanford University School of Medicine, 1050 Arastradero Road, Building A, Palo Alto, Stanford, CA, 94304, United States of America.
Norepinephrine (NE) modulates cognitive function, arousal, attention, and responses to novelty and stress, and it also regulates neuroinflammation. We previously demonstrated behavioral and immunomodulatory effects of beta-adrenergic pharmacology in mouse models of Alzheimer's disease (AD). The current studies were designed to block noradrenergic signaling in 5XFAD mice through (1) chemogenetic inhibition of the locus coeruleus (LC), (2) pharmacologic blocking of β-adrenergic receptors, and (3) conditional deletion of β1- or β2-adrenergic receptors (adrb1 or adrb2) in microglia.
View Article and Find Full Text PDFNorepinephrine (NE) modulates cognitive function, arousal, attention, and responses to novelty and stress, and also regulates neuroinflammation. We previously demonstrated behavioral and immunomodulatory effects of beta-adrenergic pharmacology in mouse models of Alzheimer's disease (AD). The current studies were designed to block noradrenergic signaling in 5XFAD mice through chemogenetic inhibition of the locus coeruleus (LC), pharmacologic blocking of β-adrenergic receptors, and conditional deletion of β1- or β2-adrenergic receptors (adrb1 or adrb2) in microglia.
View Article and Find Full Text PDFExploring Journey Maps as Products From Qualitative Research: Application Through Food Insecure Veterans' Experiences.
Qual Health Res
October 2024
Michael E. DeBakey VA Medical Center (MEDVAMC), Center for Innovations in Quality, Effectiveness and Safety (IQuESt), Houston, TX, USA.
Journey maps are graphic representations of participant, user, customer, or patient experiences or "journeys" with a particular phenomenon, product, business, or organization. Journey maps help visualize complex pathways and phases in accessible, digestible ways. They also capture emotions, reactions, and values associated with the processes participants undergo, complemented by images or quotes from participants.
View Article and Find Full Text PDFNavigating the nexus: climate dynamics and microplastics pollution in coastal ecosystems.
Environ Res
July 2024
Department of Building, Civil and Environmental Engineering, Concordia University, Montreal, Quebec, H3G 1M8, Canada.
Microplastics (MPs) pollution is an emerging environmental health concern, impacting soil, plants, animals, and humans through their entry into the food chain via bioaccumulation. Human activities such as improper solid waste dumping are significant sources that ultimately transport MPs into the water bodies of the coastal areas. Moreover, there is a complex interplay between the coastal climate dynamics, environmental factors, the burgeoning issue of MPs pollution and the complex web of coastal pollution.
View Article and Find Full Text PDFThriving on novelty: Chinese students' journey to creative travel in Thailand.
Heliyon
February 2024
Department and Graduate School of Tourism Management, Chinese Culture University, No. 55, Hwa-Kang Road, Yang Ming Shan, Taipei 111-396, Taiwan.
This study explores the intersection of creative travel and flow experiences among foreign students, a topic not extensively explored in tourism research. Specifically, it examines the mediating role of flow experiences in the relationship between students' novelty-seeking behaviors and their intention to engage in creative travel. Additionally, the research investigates how familiarity with a destination moderates this relationship.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!