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Molecular docking analysis of flavonoids with aldose reductase. | LitMetric

AI Article Synopsis

Article Abstract

Diabetes mellitus is a group of metabolic disorders that has risen to become the third most common cause in humans in recent years. The development of new bioactive substances from natural sources is a relatively new area. Flavonoids are believed to have a variety of beneficial properties in nature, including anti-inflammatory, antimicrobial, anticancer, antioxidant, neuroprotective, and anti-HIV properties. 15 naturally occurring flavonoids docked with the selected target aldose reductase. We report the optimal binding of Acumitin, Agathisflavone, Agehoustin B, and alpha-Toxicarol with aldose reductase for further consideration in drug discovery for T2DM.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9722430PMC
http://dx.doi.org/10.6026/97320630018180DOI Listing

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