A protocol for a tandem Pd/Cu-catalyzed intermolecular cross-coupling cascade between -bromobenzoic acids and 2-(2-bromoaryl)-1-benzo[]imidazoles or the corresponding imidazoles is presented. The protocol provides conceptually novel and controlled access to synthetically useful -fused (benzo)imidazophenanthridine scaffolds with high efficiency, a broad substrate scope, and excellent functional group compatibility.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791681 | PMC |
| http://dx.doi.org/10.1021/acs.orglett.2c03647 | DOI Listing |
Publication Analysis
Top Keywords
tandem palladium/copper-catalyzed
4
palladium/copper-catalyzed decarboxylative
4
decarboxylative approach
4
approach benzoimidazo-
4
benzoimidazo- imidazophenanthridine
4
imidazophenanthridine skeletons
4
skeletons protocol
4
protocol tandem
4
tandem pd/cu-catalyzed
4
pd/cu-catalyzed intermolecular
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!