Lactobacillus johnsonii strain MR1, which was isolated from the cecum of a BALB/cJ mouse in an airway allergy model, can decrease allergic airway inflammation in the model upon oral administration. Long-read sequencing of this isolate, which was performed using a MinION sequencer, yielded a single, closed genome of 1,953,837 bp, with a GC content of 34.67%.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9872695 | PMC |
http://dx.doi.org/10.1128/mra.01078-22 | DOI Listing |
Pediatr Neonatol
December 2024
Department of Pediatrics, Taipei Medical University Hospital, Taipei, Taiwan; Department of Pediatrics, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; TMU Research Center for Digestive Medicine, Taipei Medical University, Taiwan. Electronic address:
Background: Supplemental oxygen impairs lung development in premature infants with respiratory distress. This study investigated the effects of maternal Lactobacillus johnsonii supplementation on hyperoxia-induced lung injury in neonatal mice.
Methods: Pregnant C57BL/6 mice received L.
Front Immunol
December 2024
Department of Microbiology and Cell Science, Genetics Institute, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL, United States.
The internalization of N6.2 extracellular vesicles (EVs) by cells results in a significant induction of the 2',5'-oligoadenylate synthetase (OAS) pathway. It also induces expression of and .
View Article and Find Full Text PDFFront Microbiol
November 2024
Department of Microbiology and Cell Science, Genetics Institute, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL, United States.
A multivariate nutritional analysis indicated that the consumption of erucic acid-rich food, a fatty acid (FA) found primarily in rapeseed and mustard oil, was positively correlated with higher counts of lactic acid bacteria (LAB). Furthermore, we showed N6.2, as well as other species of LAB tested from the former genus, were able to efficiently use erucic acid (EA) as the source of FA.
View Article and Find Full Text PDFAnim Nutr
December 2024
College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.
Delivery and weaning are major stressful events in sows and piglets, adversely affecting production and growth performance and causing economic losses to swine farms. Probiotics as safe antibiotic alternatives have great potential for use across all stages of livestock farming. Here, 18 pregnant sows from clinical farms randomly were divided into two groups: one fed a basal diet (CON group) and the other fed a basal diet plus a probiotic mixture CBB-mix (containing 1×10 CFU/g of [CJ21], 1×10 CFU/g of [BS15], and 1×10 CFU/g of [BL21]), for 20 days before delivery.
View Article and Find Full Text PDFFront Cell Infect Microbiol
December 2024
Research and Development Center, Kangpu Pharmaceutical Co., Ltd., Changde, Hunan, China.
Background: Tongxieyaofang (TXYF) was a traditional Chinese medicine (TCM) formula for the treatment of diarrhea with liver stagnation and spleen deficiency syndrome, but the potential targets and mechanisms have not been fully clarified. This study aims to explore the potential mechanisms of TXYF in alleviating diarrhea using network pharmacology and full-length 16S rRNA gene sequencing.
Methods: Network pharmacology was applied to identify bioactive compounds and potential targets involved in the role of TXYF in alleviating diarrhea.
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