What Is This Summary About?: Molds are types of fungus that can cause sickness and death. Mold infections are increasing in China. Until 2022, medicines that can effectively treat all mold infections were still lacking in China. This summary of a study originally published in the journal . The study took place in China and tested a medicine called isavuconazole on mold samples to check if isavuconazole can be used to treat mold infections. Isavuconazole became available in China in January 2022 as a capsule (a hard gel-covered pill filled with a dose of medicine) and in June 2022 as an injection or a shot.
What Were The Results?: Isavuconazole stopped the growth of most molds. Other medicines were needed at higher amounts to stop the growth of molds.
What Do The Results Of The Study Mean?: Isavuconazole is another option to treat mold infections in China.
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http://dx.doi.org/10.2217/fmb-2022-0227 | DOI Listing |
IDCases
December 2024
Department of Pharmacy, Edward Hines Jr. VA Hospital, Hines, IL, USA.
Dematiaceous molds often cause noninvasive disease but have the potential to cause disseminated infection, particularly in immunosuppressed hosts. is the most neurotropic of dematiaceous molds and is associated with brain abscesses, but disseminated infection is quite rare. Here we present a case of disseminated in a 67-year-old renal transplant recipient with multifocal soft tissue, bone and presumed central nervous system involvement.
View Article and Find Full Text PDFBMC Res Notes
January 2025
Planta Piloto de Procesos Industriales Microbiológicos (PROIMI - CONICET), Tucumán, Argentina.
Background: Postharvest lemons are affected by several fungal infections, and as alternatives to chemical fungicides for combating these infections, different microbial biocontrol agents have been studied, with the Clavispora lusitaniae 146 strain standing out. Although strain 146 has proven to be an effective agent, the influence of a microbial biological control agent on the postharvest lemon microbiome has not been studied until now. Thus, this study aimed to evaluate how the epiphytic microbiome of postharvest lemons is affected by the application of the biocontrol yeast C.
View Article and Find Full Text PDFMycopathologia
January 2025
Teikyo University Institute of Medical Mycology (TIMM), 359 Otsuka, Hachioji, Tokyo, 192-0395, Japan.
We describe a novel Malassezia species named Malassezia polysorbatinonusus, isolated from a Japanese patient with seborrheic dermatitis. The internal transcribed spacer (ITS) region of the isolate (LSEM 4845) were only 94.7% identical to those of M.
View Article and Find Full Text PDFSci Rep
January 2025
Rui Pu Agricultural Technology Co., Ltd, Hohhot, Inner Mongolia, People's Republic of China.
Duddingtonia flagrans is a nematode-trapping fungus that is widely used to control parasitic nematodes in livestock. After oral ingestion and passage through the digestive tract of animals, this microorganism captures nematodes in feces. Although many researchers have examined the safety of this fungus for humans, animals, and the environment, few reports have discussed the safety of nematode-trapping D.
View Article and Find Full Text PDFJ Microorg Control
January 2025
S&RA Center, LG H&H (LG Household & Healthcare).
With the rise of the clean beauty trend in the cosmetics and personal care industry, consumers' interest in cosmetic ingredients, especially preservatives, continues to grow. Paraben, previously the most used preservative in cosmetics, has been excluded from many products owing to its potential risks. Therefore, a movement to lower the content of various preservatives is ongoing.
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