In this work, we report the first selective, photocatalyzed [2+2]-cycloaddition of dehydroamino acids with styrene-type olefins. This simple, mild, and scalable approach relies on the use of the triplet energy transfer catalyst [Ir(dFCFppy)dtbpy]PF under visible light irradiation and provides fast access to value-added substituted strained cyclobutane α-amino acid derivatives.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732878 | PMC |
http://dx.doi.org/10.1021/acsorginorgau.2c00026 | DOI Listing |
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