AI Article Synopsis
- Atrial fibrillation (AF) significantly contributes to functional tricuspid regurgitation (TR), and the effectiveness of catheter ablation (CA) on this condition has been studied in a cohort of 2331 patients with available echocardiographic data.
- Among patients with functional TR, 64 underwent follow-up echocardiography 6-18 months after CA, showing a notable reduction in TR severity and jet area, indicating effective treatment outcomes.
- The findings suggest that the improvement in TR is related to changes in the structure and function of the right heart following ablation for AF.
Article Abstract
Background: Atrial fibrillation (AF) plays the main role in atrial functional tricuspid regurgitation (TR). However, the effectiveness of catheter ablation (CA) for atrial functional TR together with the mechanisms of improvement of atrial functional TR have not been fully evaluated.
Methods: We retrospectively investigated consecutive 2685 patients with AF who received CA from February 2004 to December 2019 in Kyoto University Hospital, Kyoto, Japan. The current study population consisted of 2331 patients with available transthoracic echocardiographic (TTE) data before CA (2110 patients without significant TR and 221 patients with significant TR). Among the 221 patients with significant TR, there were 64 patients with functional TR and follow-up TTE at 6-18 months after CA for AF, in whom we compared echocardiographic parameters from baseline to follow-up.
Results: Patients with significant TR were older, and more often women, and had more persistent AF than those without significant TR. Among the 64 patients with functional TR, TR severity and TR jet area significantly improved at follow-up (TR jet area: 5.8 [4.0-7.6] cm to 2.1 [1.1-3.1] cm, P < 0.001). Moreover, mitral regurgitation jet area, left atrial area, mitral valve diameter, right ventricular end-diastolic area, right atrial area, and tricuspid valve diameter decreased at follow-up.
Conclusions: TR severity and jet area improved after CA in patients with AF and significant TR. The improvement of TR might be associated with reverse remodeling of the right heart.
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| http://dx.doi.org/10.1007/s10840-022-01410-x | DOI Listing |
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