AI Article Synopsis
- A Delphi study was conducted with 18 global experts to develop consensus guidelines for endoscopic management of colorectal colitis-associated neoplasia (CAN), particularly focusing on high-risk variants (HR-CAN).
- Experts agreed on key definitions, assessment techniques, and resection strategies for HR-CAN, achieving consensus on all 14 statements discussed.
- Despite the low quality of existing evidence, this study marks a significant step towards creating standardized recommendations that can enhance future research and clinical practices in managing CAN.
Article Abstract
Background And Aims: Current guidelines recommend endoscopic resection of visible and endoscopically resectable colorectal colitis-associated neoplasia (CAN) in patients with inflammatory bowel disease (IBD). However, patients with high-risk CAN (HR-CAN) are often not amenable to conventional resection techniques, and a consensus approach for the endoscopic management of these lesions is presently lacking. This Delphi study aims to reach consensus among experts on the endoscopic management of these lesions.
Methods: A 3-round modified Delphi process was conducted to reach consensus among worldwide IBD and/or endoscopy experts (n = 18) from 3 continents. Consensus was considered if ≥75% agreed or disagreed. Quality of evidence was assessed by the criteria of the Cochrane Collaboration group.
Results: Consensus was reached on all statements (n = 14). Experts agreed on a definition for CAN and HR-CAN. Consensus was reached on the examination of the colon with enhanced endoscopic imaging before resection, the endoscopic resectability of an HR-CAN lesion, and endoscopic assessment and standard report of CAN lesions. In addition, experts agreed on type of resections of HR-CAN (< 20 mm, >20 mm, with or without good lifting), endoscopic success (technical success and outcomes), histologic assessment, and follow-up in HR-CAN.
Conclusions: This is the first step in developing international consensus-based recommendations for endoscopic management of CAN and HR-CAN. Although the quality of available evidence was considered low, consensus was reached on several aspects of the management of CAN and HR-CAN. The present work and proposed standardization might benefit future studies.
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| http://dx.doi.org/10.1016/j.gie.2022.12.005 | DOI Listing |
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