Cognitive performance among older adults with psychotic depression compared to non-psychotic depression.

Psychiatry Res

University of Antwerp, Collaborative Antwerp Psychiatric Research Institute, Universiteitsplein 1, Wilfijk, 2610, Belgium; Leiden University Medical Center, the Netherlands.

Published: January 2023

It remains unclear whether psychotic depression (PD) compared to non-psychotic depression (non-PD) among older adults is associated with poorer cognitive performance. For inpatients (60+) with a major depressive episode, cognitive performance in PD and non-PD (categorical) were compared as well as the relationship between symptom severity for depression and psychosis (dimensional) and cognition. Of 90 participants (on average 72.7 years old; range 60-92), 64% were female. The severity of depressive- and psychotic symptoms are both negatively associated with cognitive functioning among older adults with depression. This is of relevance for the treatment of this vulnerable group of patients.

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Source
http://dx.doi.org/10.1016/j.psychres.2022.114996DOI Listing

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