It depends. A diagnosis of chronic obstructive pulmonary disease (COPD) made using screening spirometry in patients without symptoms does not change the course of the disease or alter smoking rates (strength of recommendation [SOR]: A, preponderance of evidence from multiple randomized controlled trials [RCTs]). However, once a patient develops symptoms of lung disease, a delayed diagnosis is associated with poorer outcomes (SOR: B, cohort studies). Active case finding (including the use of spirometry) is recommended for patients with risk factors for COPD who present with consistent symptoms (SOR: C, expert opinion).
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http://dx.doi.org/10.12788/jfp.0489 | DOI Listing |
J Vasc Surg
December 2024
Department of Surgery; Baptist Health South Florida at Boca Raton Regional Hospital, Boca Raton, Florida. Electronic address:
Objective: Enhanced Recovery After Surgery (ERAS) clinical pathways have demonstrated improved perioperative outcomes after major surgery. However, its adoption within vascular surgery has been limited. In this study, we examined the impact of an ERAS protocol with multimodal anesthesia on open abdominal aortic aneurysm (AAA) repair by comparing early outcomes before and after its implementation.
View Article and Find Full Text PDFProbl Radiac Med Radiobiol
December 2024
State Institution «National Research Center for Radiation Medicine, Hematology and Oncology of the National Academy of Medical Sciences of Ukraine», 53 Yuriia Illienka Str., Kyiv, 04050, Ukraine.
The objective was to study the relationship between clinical symptoms and the functional state of the bronchopulmonary system of clean-up workers of the Chornobyl Nuclear Power Plant accident with chronic obstructive pulmonary disease in the remote post-accident period.Materials and methods. A retrospective analysis of 824 cases of COPD in male patients who underwent inpatienttreatment in the radiation pulmonology department from 2014 to 2024 was conducted.
View Article and Find Full Text PDFRedox Biol
December 2024
Clinical and Experimental Therapeutics, College of Pharmacy, University of Georgia, Augusta, GA, 30912, USA; Charlie Norwood VA Medical Center, Augusta, GA, 30912, USA; Department of Medicine, Medical College of Georgia, Augusta University, Augusta, GA, 30912, USA. Electronic address:
Emerging evidence suggests that lipid-laden macrophages (LLM) participate in lung damage in various clinical conditions. However, the mechanisms involved in LLM formation are not fully understood. In this study, we aimed to investigate the link between reactive oxygen species (ROS) and LLM formation.
View Article and Find Full Text PDFJ Electrocardiol
December 2024
Department of Chest Diseases, Faculty of Medicine, Çanakkale Onsekiz Mart University, Canakkale, Turkey.
Background: Chronic Obstructive Pulmonary Disease (COPD) is associated with left atrial (LA) dyfunction, which may contribute to adverse cardiovascular outcomes. This study investigates the predictive value of lately identified morphology-voltage-P wave duration electrocardiography (MVP ECG) score for detecting early LA dysfunction in COPD patients.
Methods: In this cross-sectional study, 101 COPD patients were enrolled.
Cureus
November 2024
General Surgery, Brookdale University Hospital Medical Center, New York, USA.
and are anaerobic bacteria rarely encountered in clinical practice, making their identification in bacteremia significant. These organisms are typically found in the human gut and oral flora and are generally considered low-virulence. However, in patients with compromised immunity or significant comorbidities, they can lead to severe infections, including bacteremia.
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