We describe the care of a transgender woman with heart failure who underwent heart-kidney transplantation. Perioperative management of hormone therapy, considerations for future gender-affirming surgeries, and psychosocial aspects of care are discussed. Interdisciplinary collaboration is essential in the treatment of patients with advanced heart failure in the setting of gender-affirming therapies. ().

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730026PMC
http://dx.doi.org/10.1016/j.jaccas.2022.06.013DOI Listing

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