AI Article Synopsis
- This systematic review and meta-analysis examined the presence of pathogens in atherosclerotic plaques of coronary arteries in patients with coronary artery disease (CAD).
- A comprehensive search was conducted on four major English databases, and the quality of the articles was assessed using a checklist from The Joanna Briggs Institute (JBI).
- The findings revealed that specific microorganisms were prevalent in the plaques, suggesting that these pathogens may play a significant role in the progression of atherosclerosis.
Article Abstract
Background: In this systematic review and meta-analysis, the existence of pathogens in atherosclerotic plaques of coronary arteries was investigated in coronary arteries diseases (CAD) patients.
Methods: This study was designed and implemented up to 31 August 2020. The findings present according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analysis) checklist. Two independent reviewers (I.RJ and S.H) performed a comprehensive search on four different English databases including PubMed, ISI, Scopus, and Embase. In order to assess the quality of the articles, a checklist prepared by The Joanna Briggs Institute (JBI) was used.
Results: Finally, 44 studies were selected. The prevalence of different microorganisms in coronary arteries were as follows: (46.2%), (43.0%), (42.8%), (29.1%), (18.9%), virus type 1 (5.9%), (42.6%), (47.6%), (43.7%), and (32.9%).
Conclusion: Based on the result of this meta-analysis, and are the most common microorganisms in atherosclerotic plaques of coronary arteries and may have an important role in the development of atherosclerosis.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731758 | PMC |
| http://dx.doi.org/10.1155/2022/8678967 | DOI Listing |
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