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| http://dx.doi.org/10.3389/fonc.2022.1090658 | DOI Listing |
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Institute of Research, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.
Basophils are the least common granulocytes, accounting for <1% of peripheral blood leukocytes. In the last 20 years, analytical tools for mouse basophils have been developed, and we now recognize that basophils play critical roles in various immune reactions, including the development of allergic inflammation and protective immunity against parasites. Moreover, the combined use of flow cytometric analyses and knockout mice has uncovered several progenitor cells committed to basophils in mice.
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