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Herein, we describe the synthesis and characterization of fused pyrroles in cholestane and norcholestane side chains derived from kryptogenin and diosgenin, respectively. Both conventional and microwave heating techniques were used to synthesize the steroidal pyrroles from primary amines, with the microwave method producing the highest yields. In particular, the norcholestane pyrroles were tested as acaricides against the two-spotted spider mite ( Koch) under laboratory conditions and as plant growth promoters on habanero pepper ( Jacq) under greenhouse conditions.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737654 | PMC |
| http://dx.doi.org/10.3390/molecules27238466 | DOI Listing |
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Article Synopsis
- The study focuses on synthesizing two new compounds called pentafluorophenyl-N-confused porphyrins (PFNCPs), one with acetylacetonate and the other with ylidene-2-propanone, through a simple one-pot reaction without a catalyst.
- The research demonstrates that the acetylacetonate-substituted PFNCP undergoes chemical changes under mild acidic conditions, producing a new derivative when chelated with boron, while the other compound shows a unique electrocyclic reaction resulting in a tricyclic product.
- Characterization of these compounds was achieved using various techniques, including X-ray crystallography and spectroscopy, with additional theoretical studies conducted
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