The use of therapeutic antibodies for treating diseases in the CNS is hampered by the blood-brain barrier (BBB). In this issue, Edavettal et al. report on a novel bioengineered antibody not only capable of passing the BBB but also for intervening in pathological protein deposition and subsequent induction of clearing by microglia.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.medj.2022.11.006 | DOI Listing |
Publication Analysis
Top Keywords
blood-brain barrier
8
novel bispecific
4
bispecific antibody
4
antibody pass
4
pass blood-brain
4
barrier therapeutically
4
therapeutically engage
4
engage brain
4
brain therapeutic
4
therapeutic antibodies
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!