A neonatal case of cerebral venous sinus thrombosis with intrauterine onset after COVID-19 infection during pregnancy: Cause or coincidence?

J Stroke Cerebrovasc Dis

Department of Pediatrics, Division of Pediatric Neurology, Atatürk City Hospital, Balikesir, Turkey.

Published: February 2023

AI Article Synopsis

  • COVID-19 increases the risk of thrombotic events, especially in pregnant women who are already at a higher risk due to a hypercoagulable state.
  • Early in the pandemic, vertical transmission of COVID-19 from mother to fetus was often overlooked, but recent evidence suggests it may be more common than initially thought.
  • A case study reported a neonate diagnosed with cerebral venous sinus thrombosis and chronic hemorrhagic ischemia, believed to have developed in utero due to the mother's COVID-19 infection during the third trimester.

Article Abstract

Coronavirus 19 disease (COVID-19) is known to predispose patients to increased thrombotic events and the risk is higher in pregnancy which is already a hypercoagulable state. Vertical transmission of the disease during pregnancy was neglected according to data early in the pandemic, however, despite conflicting results from different studies, there is an increasing suspicion of vertical transmission with the rise of new fetal and neonatal cases and perinatal transmission can be higher than expected. An early term neonate, with the history of maternal COVID-19 infection in the start of third trimester, was diagnosed as cerebral venous sinus thrombosis and chronic hemorrhagic ischemia, with intrauterine onset.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715493PMC
http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2022.106922DOI Listing

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