Two models of hope have predominated in the literature pertaining to cancer-Snyder's "Hope Theory" and Herth's hope model-both of which have produced brief self-report measures. Growing evidence demonstrates that hope, as operationalized in these models, is associated with a number of psychological variables in individuals with cancer, including depression, distress, coping, symptom burden, and posttraumatic growth. Emerging evidence also suggests that hope may predict probability of survival in advanced cancer. Surveys show that patients and families generally prefer healthcare communication that authentically conveys prognosis; such communication is not associated with decreased hope, but may actually foster hope. Finally, several interventions have been developed to enhance hope in people with cancer, which generally demonstrate medium effects.
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http://dx.doi.org/10.1016/j.copsyc.2022.101506 | DOI Listing |
Purpose: overexpression/amplification in wild-type (WT) metastatic colorectal cancer (mCRC; human epidermal growth factor receptor 2 [HER2]-positive mCRC) appears to be associated with limited benefit from anti-EGFR antibodies and promising responses to dual-HER2 inhibition; however, comparative efficacy has not been investigated. We conducted a randomized phase II trial to evaluate efficacy and safety of dual-HER2 inhibition against standard-of-care anti-EGFR antibody-based therapy as second/third-line treatment in HER2-positive mCRC.
Methods: Patients with -WT mCRC after central confirmation of HER2 positivity (immunohistochemistry 3+ or 2+ and in situ hybridization amplified [HER2/CEP17 ratio >2.
Community Ment Health J
January 2025
Department of Social Work, Ben Gurion University of the Negev, Be'er Sheva, Israel.
A major component of recovery is the inclusion of lived experience to transform the culture of Mental Health (MH) services. In Israel lived experience has been increasingly integrated into services through peer roles. However, lived experience knowledge and expertise has not been sufficiently nor systematically integrated into the design of mental health research.
View Article and Find Full Text PDFHernia
January 2025
Department of Surgery, Baptist Health South Florida, Miami, FL, USA.
Background: Available reports of surgeon efficiency when transitioning from laparoscopic to robotic-assisted (RA) inguinal hernia repair (IHR) are retrospective or describe single-center experience. The purpose of this study is to provide a prospective, multi-surgeon, multi-center assessment of surgeon efficiency when transitioning from Lap-IHR to RA-IHR.
Methods: General surgeons with Lap-IHR experience (≥300 Lap-IHRs prior to the study) but with no robotic experience (no RA cases one year prior to the study) consented to participate in this prospective, observational pilot study of their surgical efficiency as they adopted RA-IHR.
Cancer Discov
January 2025
Department of Computer Science and Engineering, University of California, San Diego, La Jolla, California.
As the field of artificial intelligence evolves rapidly, these hallmarks are intended to capture fundamental, complementary concepts necessary for the progress and timely adoption of predictive modeling in precision oncology. Through these hallmarks, we hope to establish standards and guidelines that enable the symbiotic development of artificial intelligence and precision oncology.
View Article and Find Full Text PDFJ Am Coll Health
January 2025
Department of Counseling, University of Montana, Missoula, Montana, USA.
: In this study, we evaluated the effects of a semester-long, multi-component positive psychology course on undergraduate well-being, mental health, and physical health. : Using a quantitative, quasi-experimental, pretest-posttest design, participants in the positive psychology course ( = 38) were compared to a control condition ( = 41) on measures of well-being, physical health, and mental health. The positive psychology course included traditional lectures, experiential homework, small group labs, and individual consultations.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!