Individuals diagnosed with schizophrenia spectrum disorders (SSD) exhibit a constellation of sensory and perceptual impairments, including hyporeactivity to external input. However, individuals with SSD also report subjective experiences of sensory flooding, suggesting sensory hyperexcitability. To identify the extent to which behavioural indices of hyperexcitability are related to non-psychotic symptoms of schizophrenia, we tested a non-clinical population measured for schizophrenia-like traits (schizotypy), and a behavioural measure of sensory hyperexcitability, specifically the number of illusions seen in the Pattern Glare Test. Two samples totaling 913 individuals completed an online version of the Schizotypal Personality Questionnaire - Brief Revised (SPQ-BR) and the Pattern Glare Test. Individuals with higher schizotypy traits reported more illusions in the Pattern Glare Test. Additionally, one of the three SPQ-BR factors, the disorganized factor, significantly predicted the number of illusions reported. These data illustrate the potential for research in non-clinical samples to inform clinically relevant research.
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http://dx.doi.org/10.1111/ejn.15886 | DOI Listing |
Cureus
November 2024
Department of Optometry, Noor Alyemen Eye and E.N.T Consulting Center, Sana'a, YEM.
Keratoconus is a bilateral eye anomaly in which the cornea develops gradually, becoming steeper and thinner, causing irregular astigmatism and myopia. This unique case report highlights an atypical retinoscopic reflex that can be observed in the initial stages of keratoconus. While the reflex deviates subtly from the normal form, exhibiting a slightly distorted, irregular, and non-scissoring pattern, it differs significantly from the well-documented "scissor reflex," which is characteristic of moderate to advanced stages.
View Article and Find Full Text PDFCureus
November 2024
Family Medicine and Primary Care Department, King Abdulaziz Medical City Riyadh, Riyadh, SAU.
Background Computer vision syndrome (CVS) is a common condition affecting individuals who spend prolonged periods using electronic devices. It is characterized by symptoms such as eye strain, dryness, headaches, and neck pain. This study aims to assess the prevalence of CVS symptoms among healthcare professionals, their awareness of the condition, and the effectiveness of various preventative practices.
View Article and Find Full Text PDFNeurol Int
November 2024
School of Computer Science, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
Background/objectives: Pattern glare, associated with cortical hyperexcitability, induces visual distortions and discomfort, particularly in individuals susceptible to migraines or epilepsy. While previous research has primarily focused on transient EEG responses to patterned stimuli, this study aims to investigate how continuous presentation of pattern-glare stimuli affects neural adaptation over both fine (seconds) and coarse (entire experiment) temporal scales.
Methods: EEG recordings were obtained from 40 healthy participants exposed to horizontal square-wave gratings at three spatial frequencies presented continuously for three seconds each across multiple trials.
Purpose: To evaluate range of visual acuity, visual quality, and safety of the IC-8 small-aperture (SA) intraocular lens (IOL) (Apthera; Bausch & Lomb, Inc) in patients with cataract.
Methods: This was a prospective, multicenter, open-label, parallel-group, non-randomized, examiner-masked, 12-month clinical study conducted at 21 sites in the United States. Included patients (N = 453) received either the SA IOL (targeted to -0.
BMJ Open
November 2024
Pain Management Research Institute, Kolling Institute, Sydney Medical School, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.
Introduction: In light of the risks of over-reliance on opioid analgesia during recovery from rib fractures, there is increased interest in the efficacy of non-pharmacological approaches to pain management. This paper describes the protocol for a double-blind randomised controlled trial to evaluate the efficacy of an mHealth intervention for reducing pain intensity, pain-related distress and opioid use during early recovery from rib fractures.
Methods And Analysis: Adults (N=120) with isolated rib fractures will be recruited within 24 hours of admission to a large public hospital in Sydney, Australia (single site), and randomised (1:1 allocation) to an intervention or active control group.
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