Subsequently to the publication of this paper, an interested reader drew to the authors' attention that, on p. 2174 in the Materials and methods section (subsection ""), the sequence presented for the shRNA targeting the gene appeared to conform with the sequence that would have been predicted to target , according to a blastn search. The authors have checked their original paper, and realize that the sequence of this shRNA was written incorrectly in the paper; the sequence for the shRNA targeting the gene should have been written as: GCTTGCACTCACATACCAGTTCTCGAG- AACTGGTATGTGAGTGCAAGC. Furthermore, the published version of Fig. 5A on p. 2178 contained a pair of overlapping panels, such that data were apparently derived from the same original source even though they were intended to show the results from differently performed experiments. After having re‑examined their original data, the authors have realized that a pair of data panels were inadvertently incorporated into this figure incorrectly; specifically, the centre panel of the Lv‑shCon group and the right‑hand panel of the Lv‑shNOB1 group. The revised version of Fig. 5, showing the correct images for the abovementioned pair of data panels in Fig. 5A, is shown opposite. Note that these errors did not significantly affect either the results or the conclusions reported in this paper, and all the authors agree to this corrigendum. Furthermore, the authors thank the Editor of for allowing them the opportunity to publish this corrigendum, and apologize to the readership for any inconvenience caused. [Molecular Medicine Reports 9: 2173‑2179, 2014; DOI: 10.3892/mmr.2014.2119].
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813553 | PMC |
http://dx.doi.org/10.3892/mmr.2022.12909 | DOI Listing |
Cytojournal
November 2024
Department of Gynaecology and Obstetrics, The 960th Hospital of the Joint Logistics Support Force of the People`s Liberation Army of China, Jinan, China.
Objective: Endometrial cancer (EC) is a common gynecological malignancy, and its metastasis is one of the primary causes of treatment failure. Immunoglobulin superfamily member 1 (IGSF1), a membrane protein, has been associated with the aggressiveness and metastatic capability of various cancers. However, the role and mechanism of this protein in EC remains unclear.
View Article and Find Full Text PDFFront Biosci (Landmark Ed)
December 2024
Department of Pathology, The First Affiliated Hospital of Soochow University, 215123 Suzhou, Jiangsu, China.
Background: Psoriasis is a chronic and incurable skin inflammation driven by an abnormal immune response. Our study aims to investigate the potential of interferon-γ (IFN-γ) primed mesenchymal stem cells (IMSCs) in targeting T cells to attenuate psoriasis-like inflammation, and to elucidate the underlying molecular mechanism involved.
Methods: Mesenchymal stem cells (MSCs) were isolated from the umbilical cord and identified based on their surface markers.
Can J Gastroenterol Hepatol
December 2024
Department of Infectious Diseases, Songjiang Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Aims: Carboxylesterase (Ces)1f is implicated in protection against hepatic inflammation, but it is unclear whether the enzyme has an influence in polarization of Kupffer cells (KCs), the innate immune cells mediating hepatic inflammatory injury including acute liver failure (ALF). In the present study, we aim to explore KC polarization induced by Ces1f in mice with lipopolysaccharide/D-galactosamine (LPS/D-GalN)-induced ALF. We adopted a novel delivery system, β-1,3-D-glucan-encapsulated Endoporter-siRNA particles, to specifically target KC Ces1f knockdown via tail vein injection in mice.
View Article and Find Full Text PDFJ Orthop Surg Res
December 2024
Department of Cardiology, Qingdao Municipal Hospital, 1 Jiaozhou Road, Qingdao, Shandong, 266000, China.
An improved understanding of the molecular actions underpinning bone marrow mesenchymal stem cell (BMSC) differentiation could highlight new therapeutics for osteoporosis (OP). Current evidence indicates that microRNAs (miRNAs) exert critical roles in many biological systems, including osteoblast differentiation. In this study, we examined miR-468-3p effects on osteogenic differentiation (OD).
View Article and Find Full Text PDFFree Radic Biol Med
December 2024
Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, China. Electronic address:
Background: Lipotoxicity is a significant factor in the pathogenesis of diabetic cardiomyopathy (DbCM), a condition characterized by mitochondrial fragmentation and pyroptosis. Mitochondrial fission protein 1 (FIS1) plays a role in mitochondrial fission by anchoring dynamin-related protein 1 (DRP1). However, the specific contribution of FIS1 to DbCM remains unclear.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!