The contraction of the detrusor muscle causes the urinary bladder and its mass peristaltic movement, leading to micturition. The vesical plexus of nerves, composed of fibers from the inferior hypogastric plexus, supplies the urinary bladder. The brain plays a crucial part in developing and maintaining bladder control, although its specific involvement in urgency and urine leakage is not well understood. The critical components in the neural control of the bladder and its regulation are the pontine micturition center (located in the mediodorsal aspect of the pons) and the Onuf's nucleus, also known as the sacral micturition center (located between the sacral S2 and S4 segments). The most important cause of a neurogenic bladder is damage or lesions of the spinal cord affecting the pontine micturition center, Onuf's nucleus, or damage to the motor neurons between the pontine and the sacral centers of micturition. Neurogenic bladder can be of several types based on the location of the lesions, such as the autonomous bladder, spastic bladder, atonic bladder, and cortical bladder, all were presented with a unique clinical picture. The classical approach to a case of neurogenic bladder involves a complete assessment of the neurologic system and of pelvic anatomy, while neurogenic bladder rehabilitation may include a bladder retraining program involving intermittent catheterization, timed voiding, medications, and lifestyle modifications. This review article attempts to correlate the neurogenic bladder with various anatomical aspects related to the micturition center in the brain and spinal cord and their control over the urinary bladder, as well as the classical approach toward such a case of neurogenic bladder.
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http://dx.doi.org/10.7759/cureus.31165 | DOI Listing |
Objectives: To assess long-term outcomes (up to 10 cycles) of repeated intradetrusor botulinum toxin (BoNT) utilisation in multiple sclerosis (MS) and idiopathic overactive bladder (OAB).
Materials And Methods: This is a retrospective, international, multi-centre, observational cohort study of patients diagnosed with MS and neurogenic OAB and treated with intradetrusor BoNT between January 2005 and January 2020 (just prior to COVID-19 interruption). Dose, efficacy, duration of effect, International Consultation on Incontinence Questionnaire Overactive Bladder (ICIQ-OAB) and International Consultation on Incontinence Questionnaire Urinary Incontinence (ICIQ-UI) measures and complication rates were recorded.
Neurol Sci
January 2025
Neurology Department One, Dongfang Hospital, Beijing University of Chinese Medicine, No. 6, Fangxingyuan Community, Fangzhuang, Fengtai District, Beijing, 100078, People's Republic of China.
Background: Multiple system atrophy (MSA) is a progressive neurodegenerative disease characterized by its aggressive nature. Its main clinical features include autonomic dysfunction, Parkinson's disease, and cerebellar ataxia.
Methods: We conducted a comprehensive review of the existing literature, exploring studies and reports related to the mechanisms and treatment of multiple system atrophy related neurogenic bladder.
BJU Int
January 2025
Section of Urology, Department of Surgery, University of Chicago, Chicago, IL, USA.
Objective: To evaluate in a systematic review the outcomes, benefits, and limitations of robot-assisted surgeries for paediatric neurogenic lower urinary tract dysfunction (LUTD), as robot-assisted techniques have emerged as a potential alternative, offering enhanced precision, dexterity, and visualisation.
Methods: This review was registered in the International Prospective Register of Systematic Reviews (PROSPERO identifier CRD42023464849) and adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. We included studies of paediatric patients (aged <18 years) with neurogenic LUTD undergoing robot-assisted continence surgery, assessing safety and efficacy.
Pak J Med Sci
January 2025
Jun Zang Neurological Rehabilitation Center, Beijing Rehabilitation Hospital of Capital Medical University, Beijing 100000, Beijing, China.
Objective: To evaluate the clinical efficacy of bladder function training combined with pelvic floor biofeedback electrical stimulation in the treatment of neurogenic bladder and its impact on urodynamics.
Methods: This was a clinical comparative study. A total of 120 patients with neurogenic bladder after spinal cord injury admitted to Beijing Rehabilitation Hospital of Capital Medical University and Beijing Shijingshan Hospital from January 2023 to December 2023 were randomly divided into two groups (n= 60/group).
Cureus
December 2024
Internal Medicine, Cooper University Hospital, Camden, USA.
This case report presents a complex and challenging scenario of recurrent () bacteremia and tricuspid valve endocarditis in a 77-year-old male patient with multiple comorbidities and indwelling medical devices. The patient's medical history was significant for T4 paraplegia, neurogenic bladder requiring a chronic indwelling suprapubic catheter, heart block status post-permanent pacemaker placement, type 2 diabetes mellitus, chronic kidney disease, and chronic sacral wounds. The case highlights the difficulties in managing antibiotic-resistant infections, particularly in patients with implantable devices and chronic wounds.
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