AI Article Synopsis
- A low-cost hydrothermal method was used to synthesize pure ZnZrO and chitosan-supported ZnZrO/CS nanocomposites, which were analyzed using various techniques for their structural and morphological properties.
- The ZnZrO/CS sensor demonstrated impressive electrocatalytic activity for glucose and hydrogen peroxide detection, with high sensitivity, wide detection ranges, and low limits of detection (LOD) for both substances.
- This multifunctional electrochemical sensor exhibited excellent catalytic activity, anti-interference capabilities, and was tested successfully for glucose detection in human blood serum and hydrogen peroxide in HeLa cells.
Article Abstract
In this work, pure ZnZrO and chitosan supported (ZnZrO/CS) nanocomposite have been synthesized at low coast by hydrothermal method. FT-IR, Micro Raman, PXRD, HR-SEM-EDAX, HR-TEM, AFM, BET and XPS were used to analyze the structural and morphological properties of the fabricated nanocomposites. The fabricated ZnZrO and ZnZrO/CS nanocomposites were measured for their electrocatalytic activity towards glucose and hydrogen peroxide determinations. The ZnZrO/CS sensor exhibited wide detection range (5 μM to 5.85 mM), high sensitivity (6.78 μA mM cm), LOD (2.31 μM), and long-term stability for glucose detection in alkaline solution. Also, as a multifunctional electrochemical sensor, ZnZrO/CS sensor exhibits excellent sensing ability towards hydrogen peroxide, with a wide dynamic range (20 μM to 6.85 mM), a high sensitivity (2.22 μA mM cm), and a LOD (2.08 μM) (S/N = 3). The electrochemical measurement shows that the ZnZrO/CS sensor has excellent catalytic activity and a much LOD than ZnZrO. The modified electrode showed excellent anti interference nature. Furthermore, this ZnZrO/CS electrode was used to detection of glucose and HO in human blood serum and HeLa cells respectively.
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| http://dx.doi.org/10.1016/j.ijbiomac.2022.11.318 | DOI Listing |
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