We present psychometric evidence for the BFAS-40, an abbreviated measure of the Big Five Aspects Scale (DeYoung et al., 2007). In Study 1, we developed the BFAS-40 using metaheuristic algorithms and cross-validated the factor structure of the shortened measure. In Study 2, we demonstrated that the BFAS and BFAS-40 correlate with external criteria in similar ways. In Studies 3 and 4, we provide convergent validity evidence by examining correlations between the BFAS-40 and other measures of typical and clinically relevant personality. Finally, in Study 5, we provide evidence of test-retest reliability as well as additional construct validity evidence. Across these five studies, we demonstrate that the BFAS-40 is a short, reliable, and valid measure of the Big Five Aspects.
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http://dx.doi.org/10.1080/00223891.2022.2153690 | DOI Listing |
Mol Neurodegener
January 2025
College of Life Sciences and Oceanography, Brain Disease and Big Data Research Institute, Shenzhen University, Shenzhen, 518060, Guangdong, China.
Background: Astrocytes, the most abundant glial cell type in the brain, will convert into the reactive state in response to proteotoxic stress such as tau accumulation, a characteristic feature of Alzheimer's disease (AD) and other tauopathies. The formation of reactive astrocytes is partially attributed to the disruption of autophagy lysosomal signaling, and inhibiting of some histone deacetylases (HDACs) has been demonstrated to reduce the molecular and functional characteristics of reactive astrocytes. However, the precise role of autophagy lysosomal signaling in astrocytes that regulates tau pathology remains unclear.
View Article and Find Full Text PDFOccup Environ Med
January 2025
Lifestyles and Living Environments Unit, Finnish Institute for Health and Welfare, Oulu, Finland.
Objective: To assess the role of occupational noise exposure on pregnancy complications in urban Nordic populations.
Methods: A study population covering five metropolitan areas in Denmark, Finland, Norway and Sweden was generated using national birth registries linked with occupational and residential environmental exposures and sociodemographic variables. The data covered all pregnancies during 5-11 year periods in 2004‒2016, resulting in 373 184 pregnancies.
Int Immunopharmacol
January 2025
Department of Plastic Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, PR China; National Key Clinical Specialty (Wound Healing), The First Affiliate d Hospital Of Wenzhou Medical University, PR China. Electronic address:
This study aimed to investigate the effects of silicone implants on the incidence of breast cancer in rats, as well as their impact on immune surveillance mechanisms. Female SD rats were divided into three groups: a Placebo Surgery Group (PSG), a Thoracic Implant Group (TIG), and a Back Implant Group (BIG). Following the corresponding surgical procedures, we measured Secretoglobin Family 2A, Member 2(SCGB2A2) and Mucin-1 (MUC1) antigen levels using ELISA, and statistical analyses were conducted to evaluate immune responses.
View Article and Find Full Text PDFJAMA Intern Med
January 2025
Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.
Importance: The optimal antiviral drug for treatment of nonsevere influenza remains unclear.
Objective: To compare effects of antiviral drugs for treating nonsevere influenza.
Data Sources: MEDLINE, Embase, CENTRAL, CINAHL, Global Health, Epistemonikos, and ClinicalTrials.
J Pers Soc Psychol
January 2025
Department of Psychology, University of Oslo.
The role of childhood activity level in personality development is still poorly understood. Using data from a prospective study following 939 children from age 1.5 to 16.
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