This article discusses and illuminates the synergies and jeopardies or tradeoffs that exist between the 17 Sustainable Development Goals (SDGs) and net-zero or future climate protection options such as greenhouse gas removal (GGR) technologies and solar radiation management (SRM) deployment approaches, respectively. Through a large-scale expert-interview exercise (N = 125), the study finds firstly that numerous synergies and tradeoffs exist between GGR, SRM, and the SDGs. More specifically, we reveal that GGR deployment could enhance the attainment of 16 of the 17 SDGs, but this comes with possible tradeoffs with 12 of the SDGs. SRM deployment could not only enhance the attainment of 16 of the 17 SDGs, but also create possible tradeoffs with (a different) 12 SDGs. The findings further support the understanding of the complexity of SRM and GGR proposals and help policymakers and industrial pioneers understand, navigate, and benchmark between geoengineering approaches using sustainable development goals.
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http://dx.doi.org/10.1177/00368504221138443 | DOI Listing |
Alzheimers Dement
December 2024
Yale School of Public Health, New Haven, CT, USA.
Background: The Republic of Armenia is a post-Soviet, low- and middle-income country (LMIC) in the south Caucasus region with a steadily increasing aging population. The goal of this study was to provide the first look into the national cognitive health in Armenia, considering the growing burden of cognitive impairment (CI) and widespread lack of public awareness about dementia. As a component of the early detection memory screening program launched by Alzheimer's Care Armenia's Brain Health Project and funded through Davos Alzheimer's Collaborative (DAC), this study aimed to understand the prevalence of CI and associated factors across the adult population.
View Article and Find Full Text PDFCurr Pharm Des
January 2025
Department of Pharmacy, Delhi Pharmaceutical Sciences and Research University, New Delhi, India.
Background: The metal oxide nanoparticles possess unique properties such as biological compatibility, superior reactivity, and capacity to develop reactive oxygen species, due to this they have drawn significant interest in cancer treatment. The various MONPs such as cerium oxide, Copper oxide, Iron oxide, Titanium dioxide, and Zinc oxide have been investigated for several types of cancers including brain, breast, cervical, colon, leukemia, liver, lung, melanoma, ovarian, and prostate cancers. However, traditional physiochemical synthetic methods for MONPs commonly include toxic materials, a major concern that raises questions regarding their biocompatibility and safety.
View Article and Find Full Text PDFF S Rep
December 2024
Departments of Neurology, Division of Sleep Medicine, and Obstetrics & Gynecology, Michigan Medicine, Ann Arbor, Michigan.
Objective: Incorporate sleep into a novel lifestyle intervention strategy in adolescents with Emerging symptoms of polycystic ovary syndrome (E-PCOS).
Design: A single-center cohort study.
Setting: University hospital-based clinic for adolescents with PCOS.
JACS Au
November 2024
Department of Chemical Engineering, Loughborough University, Loughborough LE11 3TU, U.K.
This study leverages and upgrades the capabilities of computer-aided retrosynthesis (CAR) in the systematic development of greener and more efficient total synthetic routes for the active pharmaceutical ingredient (API) IM-204, a helicase-primase inhibitor that demonstrated enhanced efficacy against Herpes simplex virus (HSV) infections. Using various CAR tools, several total synthetic routes were uncovered, evaluated, and experimentally validated, with the goal to maximize selectivity and yield and minimize the environmental impact. The CAR tools revealed several synthetic options under different constraints, which can overperform the patented synthetic route used as a reference.
View Article and Find Full Text PDFJTCVS Open
December 2024
Department of Surgery, University of British Columbia, Vancouver, British Columbia, Canada.
Objective: The advent of video-assisted thoracoscopic surgery in Mongolia has faced funding and accessibility challenges, leading to languid adoption. A Mongolian-Canadian collaboration was inaugurated to support the development of a self-sustainable, self-governed minimally invasive thoracic surgery (MITS) program in Mongolia.
Methods: A multidisciplinary Canadian thoracic surgery team collaborated with the National Cancer Center of Mongolia Thoracic Surgery service from 2016 to 2023.
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