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Hydrochemical facies distribution, controlling mechanisms and Natural background concentrations of major pollutants in Ganga-Yamuna Interfluve Aquifer, India.
Environ Pollut
January 2025
Department of Geology, Aligarh Muslim University, Aligarh, India.
Evolution of groundwater genesis in Central Ganga Plain (CGP) is scrutinized with due consideration of hydrochemical and hydrodynamic environment within Quaternary alluviums. Wide variation in hydrochemical facies in CGP indicates a dynamic hydro-geochemical environment influenced from the seasonal rainfall, return flows, canal seepages, and anthropogenic activities. The Ca-HCO facies retaining meteoric nature is characterized by shallow water levels, high recharge rate, high hydraulic conductivity, low salinity and trace elemental load.
View Article and Find Full Text PDFUnveiling the role of saltmarshes as coastal potassium sinks: A perspective from porewater-derived potassium exchange.
Sci Total Environ
January 2025
Key Laboratory of Coastal Environment and Resources of Zhejiang Province, School of Engineering, Westlake University, Hangzhou 310024, China. Electronic address:
Saltmarshes serve as repositories for various metal species, primarily due to vegetation removal and mineralization processes. However, the significance of potassium (K), one of the three major nutrients (nitrogen, phosphorus, and K) essential for plant growth, has often been overlooked, particularly in the context of saltmarshes where the mechanisms of K transport via porewater exchange remain poorly understood. To address this knowledge gap, we conducted field observations and laboratory analysis, and developed a Rn mass balance model to quantify K fluxes via porewater exchange under physical, biological, and anthropogenic drivers.
View Article and Find Full Text PDFMorphological change in an isolated population of red squirrels () in Britain.
R Soc Open Sci
January 2025
Centre for Integrative Anatomy, Department of Cell and Developmental Biology, University College London, London WC1E 6BT, UK.
The mechanical properties of dietary items are known to influence skull morphology, either through evolution or by phenotypic plasticity. Here, we investigated the impact of supplementary feeding of peanuts on the morphology of red squirrels () from five populations in Britain (North Scotland, Borders, Jersey and two temporally distinct populations from Formby (Merseyside)). Stable isotope analysis confirmed dietary ecology in 58 specimens.
View Article and Find Full Text PDFEnhanced nano-LC-MS for analyzing dansylated oral cancer tissue metabolome dissolved in solvents with high elution strength.
Anal Chim Acta
February 2025
Department of Biochemistry and Molecular Biology, Chang Gung University, Taoyuan, 333, Taiwan; Clinical Proteomics Core Laboratory, LinKou Chang Gung Memorial Hospital, Taoyuan, 333423, Taiwan. Electronic address:
Background: Tissue metabolomics analysis, alongside genomics and proteomics, offers crucial insights into the regulatory mechanisms of tumorigenesis. To enhance metabolite detection sensitivity, chemical isotope labeling (CIL) techniques, such as dansylation, have been developed to improve metabolite separation and ionization in mass spectrometry (MS). However, the dissolution of hydrophobic derivatized metabolites in solvents with high acetonitrile content limits the use of liquid chromatography (LC) systems with small-volume reversed-phase (RP) columns.
View Article and Find Full Text PDFIntegrated transcriptomics and proteomics analysis of the impact of iodine‑125 in hepatocellular carcinoma.
Mol Med Rep
March 2025
The First Central Clinical School, Tianjin Medical University, Tianjin 300000, P.R. China.
Hepatocellular carcinoma (HCC) is a common cause of cancer‑related mortality and morbidity worldwide. While iodine‑125 (I) particle brachytherapy has been extensively used in the clinical treatment of various types of cancer, the precise mechanism underlying its effectiveness in treating HCC remains unclear. In the present study, MHCC‑97H cells were treated with I, after which, cell viability and proliferation were assessed using Cell Counting Kit‑8, 5‑ethynyl‑2'‑deoxyuridine and colony formation assays, cell invasion and migration were evaluated using wound healing and Transwell assays, and cell apoptosis was determined using flow cytometry.
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