Rosemary is one of the industrially significant crops traded over the world. Its cultivation in many countries depends on locally adapted populations rather than on the use of improved varieties. Collection and characterization of the local populations could contribute to their conservation and selection of desirable traits. Therefore, this study was undertaken to estimate the diversity of 45 rosemary accessions collected from different parts of Ethiopia using qualitative morphological traits. The frequency distribution of characters reflected the polymorphism of the studied characters, and a total of 39 phenotypic classes were observed. Shannon-weaver diversity indices estimated across accessions ranged from 0.43 to 0.99 with a mean value of 0.79, demonstrating the existence of adequate phenotypic diversity among the accessions. Estimates of diversity indices within and among growing regions revealed that intra-region diversity (0.57) exceeds inter-region diversity (0.43). Cluster analysis classified the accessions into six major clusters regardless of the accessions' geographical origin. This was consistent with the estimated within and among growing regions diversity indices. The results clearly showed the presence of considerable levels of phenotypic diversity that could be exploited as a source of a valuable gene pool for future breeding programs.
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http://dx.doi.org/10.1016/j.heliyon.2022.e11895 | DOI Listing |
Clin Rev Allergy Immunol
January 2025
Postgraduate Program in Biochemistry, Federal University of Espírito Santo (UFES), Vitória, Espírito Santo, Brazil.
Asthma is a complex disease with varied clinical manifestations resulting from the interaction between environmental and genetic factors. While chronic airway inflammation and hyperresponsiveness are central features, the etiology of asthma is multifaceted, leading to a diversity of phenotypes and endotypes. Although most research into the genetics of asthma focused on the analysis of single nucleotide polymorphisms (SNPs), studies highlight the importance of structural variations, such as copy number variations (CNVs), in the inheritance of complex characteristics, but their role has not yet been fully elucidated in asthma.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
The Mycobacterium avium complex (MAC) is a group of closely related nontuberculous mycobacteria that can cause various diseases in humans. In this study, genome sequencing, comprehensive genomic analysis, and antimicrobial susceptibility testing of 66 MAC clinical isolates from King Chulalongkorn Memorial Hospital, Bangkok, Thailand were carried out. Whole-genome average nucleotide identity (ANI) revealed the MAC species distribution, comprising 54 (81.
View Article and Find Full Text PDFJ Transl Med
January 2025
Department of Urology, The First Affiliated Hospital of Soochow University, No. 899 Pinghai Road, Suzhou, 215006, People's Republic of China.
CXCL14 is a highly conserved chemokine expressed in various cell types, playing crucial roles in both physiological and pathological processes, including immune regulation and tumorigenesis. Recently, the role of CXCL14 in tumors has attracted considerable attention. However, previous pan-cancer studies have reported inconsistencies regarding the effects of CXCL14 on tumors, particularly concerning its expression levels in tumor tissues and its influence on various phenotypes of cancer cells.
View Article and Find Full Text PDFCurr Biol
December 2024
Palaeoscience Research Centre, School of Environmental and Rural Science, University of New England, Armidale, NSW 2351, Australia.
Predation is an important driver of species-level change in modern and fossil ecosystems, often through selection for defensive phenotypes in prey responding to predation pressures over time. Records of changes in shell morphology and injury patterns in biomineralized taxa are ideal for demonstrating such adaptive responses. The rapid increase in diversity and abundance of biomineralizing organisms during the early Cambrian is often attributed to predation and an evolutionary arms race.
View Article and Find Full Text PDFAging (Albany NY)
January 2025
Department of Public Health Sciences, University of Chicago, Chicago, IL 60615, USA.
Background: DNA methylation (DNAm) data from human samples has been leveraged to develop "epigenetic clock" algorithms that predict age and other aging-related phenotypes. Some DNAm clocks were trained using DNAm obtained from blood cells, while other clocks were trained using data from diverse tissue/cell types. To assess how DNAm clocks perform across non-blood tissue types, we applied DNAm algorithms to DNAm data generated from 9 different human tissue types.
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