AI Article Synopsis

  • Allergists may focus too much on oral immunotherapy (OIT) as the cause for gastrointestinal (GI) symptoms, potentially overlooking other non-OIT related issues.
  • A proposed management algorithm for handling GI symptoms during OIT is presented, designed to assist new providers like allergists and trainees who may encounter these symptoms.
  • Input from various allergy clinics in Canada shaped the algorithm, but more research is necessary to establish comprehensive treatment recommendations for GI symptoms in OIT patients.

Article Abstract

Allergists addressing gastrointestinal (GI) symptoms during oral immunotherapy (OIT) may be biased toward diagnoses related to OIT; however, non-OIT causes may occur. Although there is currently a lack of robust data for evidence-based treatment recommendations, we provide 3 real-world illustrative cases along with a proposed management algorithm for GI symptoms encountered during OIT. This algorithm was developed because of a significant clinical need, given the number of new-to-OIT providers that include practicing allergists, trainees transitioning into practice, and allied health care providers who manage GI symptoms in OIT patients. We developed the algorithm based on the opinions of community and academic allergy clinics across Canada with significant clinical experience offering infant, preschool, and school-aged OIT patients, with gastroenterologist input. Further research is needed to fill the knowledge gaps in the management of GI symptoms during OIT before formal recommendations can be suggested.

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Source
http://dx.doi.org/10.1016/j.jaip.2022.11.015DOI Listing

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