Helping patients control diabetes mellitus (DM) and minimize complications is the top priority for care of patients with diabetes. A retrospective review of 86 charts was conducted to investigate the impact of an 8-hour diabetic education program on glycemic control and weight in adults with type 2 DM. Hemoglobin A1C levels and weights were documented pre- and postintervention. Patients participating in the program demonstrated decreased levels of mean A1C and mean weight postintervention. Spiritual care for people living with diabetes and the use of continuous glucose monitors to improve disease management are discussed.
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http://dx.doi.org/10.1097/CNJ.0000000000001018 | DOI Listing |
Hypertens Res
January 2025
School of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan; #155 Section 2, Linong Street, Taipei, 112, Taiwan.
To explore the effects of obstructive sleep apnea (OSA) on nocturnal changes in blood pressure (BP), we enrolled 2037 participants who underwent polysomnography (PSG) between 2019 and 2020 and examined BP changes before and after sleep. BP was measured in the evening and the following morning using an electronic wrist sphygmomanometer in the supine position. The severity of OSA was determined by PSG and graded based on the apnea/hypopnea index (AHI).
View Article and Find Full Text PDFLancet Diabetes Endocrinol
January 2025
Department of Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON N6A 5B7, Canada. Electronic address:
Lancet Diabetes Endocrinol
January 2025
LIB Therapeutics, Cincinnati, OH, USA. Electronic address:
Background: Lerodalcibep, a small binding anti-PCSK9 protein (adnectin), showed effective LDL cholesterol reduction in heterozygous familial hypercholesterolaemia. We aimed to assess the safety and efficacy of lerodalcibep and evolocumab in a globally diverse homozygous familial hypercholesterolaemia population.
Methods: This phase 3, randomised, open-label, crossover, non-inferiority study consisted of two 24-week treatment periods separated by an 8-week washout.
Mol Biol Rep
January 2025
Medical Sociology and Psychobiology, Department of Health and Physical Activity, University of Potsdam, 14469, Potsdam, Germany.
Background: Depression constitutes a risk factor for osteoporosis, but underlying molecular and cellular mechanisms are not fully understood. MiRNAs influence gene expression and are carried by extracellular vesicles (EV), affecting cell-cell communication.
Aims: (1) Identify the difference in miRNA expression between depressed patients and healthy controls; (2) Analyze associations of these miRNAs with bone turnover markers; (3) Analyze target genes of differentially regulated miRNAs and predict associated pathways regarding depression and bone metabolism.
J Med Virol
February 2025
Xiangya School of Public Health, Central South University, Changsha, China.
Patients with diabetes are at increased risk of HBV infection; however, the effects of HBV infection and anti-HBV therapy on the management of type 1 diabetes (T1D), type 2 diabetes (T2D), and latent autoimmune diabetes in adults (LADA) remain unclear. From 2016 to 2023, we recruited a multicenter cohort of 355 HBV-infected inpatients, including 136 with T1D, 140 with T2D, and 79 with LADA. The control group included 525 HBV-uninfected inpatients, comparing 171 with T1D, 204 with T2D and 150 with LADA.
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