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Acrokeratosis paraneoplastica (Basex syndrome) with trachyonychia preceding the diagnosis of squamous cell carcinoma of the lung.
Dermatol Online J
April 2024
Department of Dermatology, Tulane University, New Orleans USA Department of Dermatology, Roswell Park Comprehensive Cancer Center, Buffalo USA.
Acrokeratosis paraneoplastica (Basex syndrome) is a rare paraneoplastic condition hallmarked by psoriasiform lesion development on acral surfaces, most often related to an underlying squamous cell carcinoma. Patients may also present with nail plate changes. Successful management of this condition can be accomplished by treating the underlying malignancy.
View Article and Find Full Text PDFAcrokeratosis neoplastica (Bazex syndrome): Report of two cases and literature review.
Heliyon
March 2024
Department of Legal Medicine, 6-20-2, Shinkawa, Mitaka-shi, Tokyo, 181-8611, Japan.
Article Synopsis
- The skin can indicate internal diseases, with Bazex syndrome being a specific condition that shows erythematous hyperkeratosis and yellowish scales on palms and soles.
- There is a notable link between Bazex syndrome and certain cancers, particularly squamous cell carcinomas (SCC), which raises its importance in early cancer detection.
- The text presents cases of Bazex syndrome associated with SCC in the glottis and lung, while also providing insights on the disease's clinical manifestations and pathogenesis.
[Bazex syndrome: a rare paraneoplastic disease].
Medicina (B Aires)
January 2024
Servicio de Dermatología, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
Bazex syndrome is a paraneoplastic disorder most commonly linked to squamous cell carcinomas of the upper aerodigestive tract, followed by lung cancer and other malignancies. It manifests through three stages of skin involvement that mirror the tumor's progression. Remarkably, skin lesions precede tumor symptoms or diagnosis in two-thirds of cases, underscoring the crucial role of suspecting this condition as it can promptly reveal an underlying neoplasm.
View Article and Find Full Text PDFA case of Bazex syndrome with type 2 immune response.
Eur J Dermatol
September 2022
Department of Dermatology,
Acrokeratosis Paraneoplastica (Bazex Syndrome): A Case Report.
Case Rep Dermatol
October 2022
Department of Dermatology, Kepler University Hospital Linz, Johannes Kepler University, Linz, Austria.
Acrokeratosis paraneoplastica Bazex is a rare paraneoplastic skin manifestation, typically causing acral psoriasiform lesions. Patients usually show erythematous hyperkeratosis with yellowish, adherent scales on the hands and feet or other acral locations such as ears or nose. We herein report a case of Bazex syndrome in a male patient, who was previously diagnosed with hepatocellular carcinoma.
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