AI Article Synopsis
- Cancer is the second leading cause of death globally, and immunotherapy has gained significant attention as a treatment method in recent years.
- The STING-mediated signaling pathway has a complex role in cancer, influencing different tumor types and stages in various ways.
- Research from 2008-2022 indicates a growing interest in STING signaling, particularly regarding its impact on tumor microenvironments and immunotherapy, suggesting these areas will continue to be key research focuses moving forward.
Article Abstract
Cancer, as the second leading cause of death worldwide, has become an ongoing public health challenge and its treatment has received much attention, with immunotherapy becoming a hot research topic in recent years. The interferon gene stimulating factor (STING)-mediated signaling pathway has a "double-edged sword" role in cancer, which plays different roles in different types and stages of tumors. In this paper, we discuss the current research status, cooperation, and hotspots of STING signaling pathway in cancer from 2008-2022 using CiteSpace software based on the literature of cancer and STING signaling pathway. In addition, we predicted future research trends in this field by analysis, and the results showed that the STING signaling pathway is rapidly increasing in cancer research, and its role in tumor microenvironment and immunotherapy has become a new hot spot in current research and will continue to receive high attention.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9711965 | PMC |
| http://dx.doi.org/10.1155/2022/5095176 | DOI Listing |
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