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| http://dx.doi.org/10.21037/atm-22-4930 | DOI Listing |
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GWAS analysis revealed genomic loci and candidate genes associated with the 100-seed weight in high-latitude-adapted soybean germplasm.
Theor Appl Genet
January 2025
Research Center for Life Sciences Computing, Zhejiang Lab, Hangzhou, 310012, China.
In the present study, we identified 22 significant SNPs, eight stable QTLs and 17 potential candidate genes associated with 100-seed weight in soybean. Soybean is an economically important crop that is rich in seed oil and protein. The 100-seed weight (HSW) is a crucial yield contributing trait.
View Article and Find Full Text PDFA genome-wide association study for recurrent laryngeal neuropathy in the Thoroughbred horse identifies a candidate gene that regulates myelin structure.
Equine Vet J
January 2025
UCD School of Agriculture and Food Science, University College Dublin, Dublin, Ireland.
Background: Equine recurrent laryngeal neuropathy (RLN) is an economically important upper respiratory tract (URT) disease with a genetic contribution to risk, but genetic variants independent of height have not been identified for Thoroughbreds. The method of clinical assessment for RLN is critical to accurately phenotype groups for genetic studies.
Objectives: To identify genetic risk loci for RLN in Thoroughbreds in a genome-wide association study (GWAS) following high-resolution phenotyping.
Avirulence depletion assay: Combining R gene-mediated selection with bulk sequencing for rapid avirulence gene identification in wheat powdery mildew.
PLoS Pathog
January 2025
Chair of Phytopathology, TUM School of Life Sciences, Technical University of Munich, Freising, Germany.
Wheat production is threatened by multiple fungal pathogens, such as the wheat powdery mildew fungus (Blumeria graminis f. sp. tritici, Bgt).
View Article and Find Full Text PDFWhole transcriptome analysis and construction of gene regulatory networks of granulosa cells from patients with polycystic ovary syndrome (PCOS).
Eur J Med Res
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Department of Reproductive Medicine Center, The Affiliated Hospital of Inner Mongolia Medical University, Hohhot, 010050, Inner Mongolia, China.
Objective: Polycystic ovary syndrome (PCOS) is a reproductive endocrine disease characterized by reproductive dysfunction and metabolic abnormalities. The purpose of this study was to explore the expression characteristics of coding and non-coding RNAs in granulosa cells of PCOS, and to provide data support for understanding the pathogenesis of PCOS.
Methods: Three patients with PCOS (according to the 2003 Rotterdam diagnostic criteria) and three normal controls were selected.
RBM47 promotes cell proliferation and immune evasion by upregulating PDIA6: a novel mechanism of pancreatic cancer progression.
J Transl Med
December 2024
Department of Pathology, The First Affiliated Hospital of Zhengzhou University, No. 1, Jianshe East Road, Zhengzhou, China.
Background: Pancreatic cancer (PC) is a lethal malignancy characterized by poor prognosis and high mortality. We found the highly expressed RNA-binding motif protein 47 (RBM47) in PC progression. The RBM47 expression was negatively correlated with natural killer (NK) cell infiltrate in PC.
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