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| http://dx.doi.org/10.1016/j.asjsur.2022.10.022 | DOI Listing |
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Dementia Care Research and Psychosocial Factors.
Alzheimers Dement
December 2024
Seattle University, Seattle, WA, USA.
Background: Cerebral amyloid angiopathy (CAA) and hypertension are the two most common risk factors of intracranial hemorrhage leading to cognitive impairment, but less is known about how the two relate. A better understanding of the association between these risk factors is a key step towards developing new strategies to manage hypertension and attenuate CAA progression.
Method: This study analyzed data from 2,510 participants in the National Alzheimer's Coordinating Center (NACC) dataset who had CAA and longitudinal blood pressure (BP) measurements before death.
Heart transplant survival and the use of donors with intracranial bleeding: United Network for Organ Sharing Registry propensity-score matched analysis.
JTCVS Open
December 2024
Division of Cardiovascular and Thoracic Surgery, Rabin Medical Center, Petach-Tikva, Israel.
Objective: The transplantation of hearts from donors who experienced intracranial bleeding (ICB) has been associated with inferior long-term survival in both single-center analyses and, more recently, with the United Network for Ogan Sharing Registry. The purpose of this study was to further explore this relationship through propensity score matching in recipients receiving donor hearts from ICB and non-ICB donors in a large national registry.
Methods: We performed a retrospective cohort analysis of the United Network for Organ Sharing Registry Organ Procurement and Transplantation Network between 2006 and 2018 for adult candidates wait-listed for isolated heart transplantation.
Differences in tumor size, clinical, demographic, and socioeconomic profiles of central nervous system tumors among a racially diverse cohort: A retrospective case-control study.
Surg Neurol Int
December 2024
Department of Medicine, University of Hawai'i at Mānoa, John A. Burns School of Medicine, Honolulu, Hawaii, USA.
Background: One avenue to improve outcomes among brain tumor patients involves the mitigation of healthcare disparities. Investigating clinical differences among brain tumors across socioeconomic and demographic strata, such can aid in healthcare disparity identification and, by extension, outcome improvement.
Methods: Utilizing a racially diverse population from Hawaii, 323 cases of brain tumors (meningiomas, gliomas, schwannomas, pituitary adenomas, and metastases) were matched by age, sex, and race to 651 controls to investigate the associations between tumor type and various demographic, socioeconomic, and medical comorbidities.
Spontaneous cerebrospinal fluid rhinorrhea as a primary presentation of idiopathic intracranial hypertension, management strategies, and clinical outcome.
Surg Neurol Int
December 2024
Department of Neurosurgery, Assiut University, Assiut, Egypt.
Background: Causes of cerebrospinal fluid (CSF) rhinorrhea could be divided into primary (spontaneous) and secondary (head trauma and iatrogenic). Idiopathic intracranial hypertension (IIH) has emerged as a cause for spontaneous CSF rhinorrhea but is still underestimated, may be overlooked and needs special consideration in management. The objective of this study is to demonstrate spontaneous CSF rhinorrhea as the primary presentation of IIH and explore the algorithm of management.
View Article and Find Full Text PDFCerebral compliance assessment from intracranial pressure waveform analysis: Is a positional shift-related increase in intracranial pressure predictable?
PLoS One
January 2025
Department of Intensive Care, Ramsay Générale de Santé, Hôpital privé de la Loire, Saint Etienne, France.
Real-time monitoring of intracranial pressure (ICP) is a routine part of neurocritical care in the management of brain injury. While mainly used to detect episodes of intracranial hypertension, the ICP signal is also indicative of the volume-pressure relationship within the cerebrospinal system, often referred to as intracranial compliance (ICC). Several ICP signal descriptors have been proposed in the literature as surrogates of ICC, but the possibilities of combining these are still unexplored.
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