Drugs associated adversities are common in health care practice. These adversities are often associated with the dose-related, time-related and methods of drug intake and their rationality in a given condition but can also be unrelated to either of these causes. Such unpredictable drug reactions are highly important from the perspective of safe use of a drug and to prevent complications from any such adversity which is relatively uncommon. The case reported here is a likely case of Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) like idiosyncratic adversity after oral consumption of an ayurvedic formulation containing Bhallataka (Semecarpus anacardium). DRESS is found associated with many other classes of drugs but its association with ayurvedic drug has not yet been reported. Upon Naranjo probability scale the event scored 6, putting it into the category of probable drug related adversity. This report widens our understanding towards the possibility of delayed and idiosyncratic drug adversities upon the consumption of certain ayurvedic drugs.
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http://dx.doi.org/10.1016/j.jaim.2022.100635 | DOI Listing |
J Ayurveda Integr Med
November 2024
Bharatiya Sanskriti Darshan Trust's Integrated Cancer Treatment and Research Centre, Kesnand Road, Wagholi, Pune, Maharashtra, 412207, India.
Background: The rising prevalence of colorectal cancer (CRC) may be attributed to various nutritional and behavioural factors, making both factors as important topics for discussion to the layman and the oncology community.
Objective: To explore additional dietary risk factors, other than those already known, according to the Ayurvedic perspective in CRC patients.
Methods: Detail dietary data was collected from 420 patients of CRC and 116 healthy volunteers registered at our institute with the help of a food frequency questionnaire.
J Health Popul Nutr
November 2024
Institute of Primary Care, University of Zurich, Zurich, Switzerland.
J Chromatogr B Analyt Technol Biomed Life Sci
October 2024
Drugs Testing Laboratory Avam Anusandhan Kendra, Raipur, Chhattisgarh 402010, India. Electronic address:
Background: Prameha was identified in 1552 BCE as a Maharoga (major disease), one of the eight grave diseases of Ancient medical history. Initial days of recognition labeled Prameha as a rich man's disease, as found prevalent among people of higher socio-economic background. This fact was thereby linked with the diagnosis of diabetes and the invention of iron in the Iron Age, as wealthy part of the population who initiated consumption of newly harvested rice and wheat were found majorly diagnosed.
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July 2024
Clinical Research, M V Hospital and Research Centre, Lucknow, Uttar Pradesh, 226003, India.
Background: Ashwagandha is a well-known Ayurvedic herb used for youthful vigor and wellbeing. This study investigated the effects of 600 mg standardized root extract (>5% withanolides) of Ashwagandha ( ) on muscle size, strength and cardiorespiratory endurance following resistance training.
Methods: In this eight-week, parallel-group, multicenter, randomized, double-blind, placebo-controlled clinical study, 80 healthy male and female participants aged 18-45 years, who engaged in regular physical activity were randomly allocated in a 1:1 ratio to receive Ashwagandha (AG, n=40) 300 mg capsules twice daily for eight weeks, or identical placebo (PB, n=40).
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