Idiosyncratic adversity reported after oral consumption of an ayurvedic formulation containing bhallataka (Semecarpus anacardium): A case report.

J Ayurveda Integr Med

Ayurveda-Arthritis Treatment and Advanced Research Center (A-ATARC), State Ayurvedic College and Hospital, Lucknow University, Lucknow 226003.

Published: November 2022

Drugs associated adversities are common in health care practice. These adversities are often associated with the dose-related, time-related and methods of drug intake and their rationality in a given condition but can also be unrelated to either of these causes. Such unpredictable drug reactions are highly important from the perspective of safe use of a drug and to prevent complications from any such adversity which is relatively uncommon. The case reported here is a likely case of Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) like idiosyncratic adversity after oral consumption of an ayurvedic formulation containing Bhallataka (Semecarpus anacardium). DRESS is found associated with many other classes of drugs but its association with ayurvedic drug has not yet been reported. Upon Naranjo probability scale the event scored 6, putting it into the category of probable drug related adversity. This report widens our understanding towards the possibility of delayed and idiosyncratic drug adversities upon the consumption of certain ayurvedic drugs.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713265PMC
http://dx.doi.org/10.1016/j.jaim.2022.100635DOI Listing

Publication Analysis

Top Keywords

consumption ayurvedic
12
idiosyncratic adversity
8
oral consumption
8
ayurvedic formulation
8
formulation bhallataka
8
bhallataka semecarpus
8
semecarpus anacardium
8
drug
7
adversity reported
4
reported oral
4

Similar Publications

Background: The rising prevalence of colorectal cancer (CRC) may be attributed to various nutritional and behavioural factors, making both factors as important topics for discussion to the layman and the oncology community.

Objective: To explore additional dietary risk factors, other than those already known, according to the Ayurvedic perspective in CRC patients.

Methods: Detail dietary data was collected from 420 patients of CRC and 116 healthy volunteers registered at our institute with the help of a food frequency questionnaire.

View Article and Find Full Text PDF
Article Synopsis
  • * This review compares the effectiveness of several dietary supplements, including red yeast rice, flaxseed, artichokes, and bergamot, against statins, based on studies published from 2012 to 2024.
  • * Findings indicate that supplements can lower cholesterol, but further research is needed to confirm their efficacy and quality, particularly for red yeast rice, bergamot, and flaxseed.
View Article and Find Full Text PDF

Development of a simple and reproducible HPTLC method on protective effect induced by bark of Acacia nilotica on poisoning caused by use of nicotine containing tobacco products.

J Chromatogr B Analyt Technol Biomed Life Sci

October 2024

Drugs Testing Laboratory Avam Anusandhan Kendra, Raipur, Chhattisgarh 402010, India. Electronic address:

Article Synopsis
  • Tobacco products present significant global public health challenges, primarily due to nicotine's addictive properties and withdrawal effects.
  • Researchers utilize laboratory animals to study nicotine's toxicity, dependence, and the potential protective effects of various substances, including Babbul (Acacia nilotica Linn.).
  • A specific in-vitro study demonstrated that Acacia nilotica extracts can reduce nicotine concentrations by 39.12%, highlighting its potential as a protective agent against nicotine poisoning from tobacco use.
View Article and Find Full Text PDF

Background: Prameha was identified in 1552 BCE as a Maharoga (major disease), one of the eight grave diseases of Ancient medical history. Initial days of recognition labeled Prameha as a rich man's disease, as found prevalent among people of higher socio-economic background. This fact was thereby linked with the diagnosis of diabetes and the invention of iron in the Iron Age, as wealthy part of the population who initiated consumption of newly harvested rice and wheat were found majorly diagnosed.

View Article and Find Full Text PDF

Background: Ashwagandha is a well-known Ayurvedic herb used for youthful vigor and wellbeing. This study investigated the effects of 600 mg standardized root extract (>5% withanolides) of Ashwagandha ( ) on muscle size, strength and cardiorespiratory endurance following resistance training.

Methods: In this eight-week, parallel-group, multicenter, randomized, double-blind, placebo-controlled clinical study, 80 healthy male and female participants aged 18-45 years, who engaged in regular physical activity were randomly allocated in a 1:1 ratio to receive Ashwagandha (AG, n=40) 300 mg capsules twice daily for eight weeks, or identical placebo (PB, n=40).

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!