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Objective: Aim: Using morphometric methods to study the features of endotheliocyte remodeling of the arterial and venous beds of the testicles during long-term ethanol intoxication.
Patients And Methods: Materials and Methods: Endotheliocytes of the arterial and venous bed of the left and right testes of 60 white male rats, which were divided into two groups, were morphologically studied. The 1 group consisted of 30 intact animals, the 2 - 30 rats, which were daily intragastrically injected with a 30 % ethanol solution at the rate of 2 ml per 100 g of the animal's weight for 28 days.
Ethyl alcohol consumption characteristics of deceased individuals in Lithuania.
J Forensic Leg Med
November 2024
Faculty of Medicine, Vilnius University, Vilnius, M. K. Ciurlionio str. 21, Lithuania.
Article Synopsis
- Alcohol-related deaths in Lithuania decreased by nearly one-third over the past decade but have increased since 2019, with a study analyzing 1,200 autopsies from 2018 to 2022 uncovering rising trends.
- The main causes of death identified were diseases (54.17%), accidents (31.25%), suicides (12.08%), and homicides (2.5%), with toxicology tests finding a significant link between higher blood alcohol concentrations and victims of accidents.
- The research highlights the role of alcohol intoxication in fatalities, emphasizing its impact on deaths from accidents and homicides, while also revealing differences in intoxication levels between genders.
Cytologic features of gastric-type endocervical adenocarcinoma: Three cases report and literature review.
Medicine (Baltimore)
October 2024
Department of Pathology, Yueyang Central Hospital, Yueyang City, Hunan Province, China.
Rationale: Cervical gastric-type adenocarcinoma shows gastric differentiation, and the tumor cell morphology appears benign and unrelated to human papillomavirus, which makes cervical gastric-type adenocarcinoma highly susceptible to misdiagnosis as normal glandular epithelium in cytologic diagnosis.
Patient Concerns: We present 3 cases of gastric-type adenocarcinoma, with the first being a 57-year-old female with abnormal uterine bleeding and fluid drainage. The second patient was a 63-year-old female, and the third was a 59-year-old female with irregular vaginal bleeding after menopause.
Microglia: The Drunken Gardeners of Early Adversity.
Biomolecules
August 2024
Department of Psychiatry, Yale University School of Medicine, 300 George Street, Suite 901, New Haven, CT 06511, USA.
Early life adversity (ELA) is a heterogeneous group of negative childhood experiences that can lead to abnormal brain development and more severe psychiatric, neurological, and medical conditions in adulthood. According to the immune hypothesis, ELA leads to an abnormal immune response characterized by high levels of inflammatory cytokines. This abnormal immune response contributes to more severe negative health outcomes and a refractory response to treatment in individuals with a history of ELA.
View Article and Find Full Text PDF[Forensic toxicological characteristics of modern occupational injuries].
Sud Med Ekspert
August 2024
Bureau of Forensic Medical Expertise of Moscow Healthcare Department, Moscow, Russia.
Article Synopsis
- - The study focused on analyzing the role of alcohol and drug intoxication in fatal workplace injuries and sudden deaths among employees in Moscow, investigating 357 cases in 2023 with an average age of around 48 years, predominantly involving men (92.4%).
- - It was found that 15% of the deceased had ethanol in their blood, while 6.7% had narcotic drugs or psychotropic medications, with chronic intoxication playing a significant role in 70% of cardiomyopathy cases.
- - The research highlights the need for measures to reduce occupational mortality related to substance use, noting that nearly 24% of accidents occurred in industrial or construction settings influenced by alcohol.
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