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http://dx.doi.org/10.1055/a-1974-9255 | DOI Listing |
Neurogastroenterol Motil
March 2025
Department of Gastroenterology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, P. R. China.
Backgrounds And Aims: Achalasia is an acquired esophageal neurodegenerative disorder, characterized by selective loss of inhibitory neurons in the myenteric plexus of the lower esophageal sphincter (LES). The Enteric neural precursor cell (ENPC) is essential in maintaining neurogenesis, but its role in achalasia pathogenesis is unknown. This study aimed to explore the neurogenesis status in the LES among achalasia patients.
View Article and Find Full Text PDFGut Liver
March 2025
Division of Gastroenterology and Hepatology, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Pyloric dysfunction is defined as hypertonia or spasm of the pyloric sphincter. The pylorus plays a key role in gastric emptying, but its function remains incompletely understood. Most studies have focused on gastroparesis regardless of the underlying pathophysiology.
View Article and Find Full Text PDFEndoscopy
December 2025
Department of Gastroenterology, People's Hospital of Leshan, Southwest Medical University, Leshan, China.
Gastrointest Endosc
March 2025
Department of Gastroenterology and Hepatology, Austin Health, The University of Melbourne, Victoria, Australia.
Gastrointest Endosc
February 2025
Johns Hopkins Medicine, Baltimore, MD, USA. Electronic address:
Background And Aims: Zenker's peroral endoscopic myotomy (Z-POEM) has demonstrated excellent technical and clinical success. However, the remnant mucosal flap can result in symptom recurrence. In addition, mucosal closure can be technically challenging.
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