Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.23736/S2724-5276.22.07100-2 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Multiomics in cancer biomarker discovery and cancer subtyping.
Adv Clin Chem
January 2025
School of Biosystem and Biomedical Science, College of Health Science, Korea University, Seoul, Republic of Korea; Department of Integrated Biomedical and Life Science, Korea University, Seoul, Republic of Korea; BK21FOUR R&E Center for Learning Health Systems, Korea University, Seoul, Republic of Korea; L-HOPE Program for Community-Based Total Learning Health Systems, Korea University, Seoul, Republic of Korea. Electronic address:
The advent of multiomics has ushered in a new era of cancer research characterized by integrated genomic, transcriptomic and proteomic analysis to unravel the complexities of cancer biology and facilitate the discovery of novel biomarkers. This chapter provides a comprehensive overview of the concept of multiomics, detailing the significant advances in the underlying technologies and their contributions to our understanding of cancer. It delves into the evolution of genomics and transcriptomics, breakthroughs in proteomics, and overarching progress in multiomic methodologies, highlighting their collective impact on cancer biomarker discovery.
View Article and Find Full Text PDFTherapeutic effects of fumaric acid on proteomic expression and gut microbiota composition in Pacific white shrimp (Penaeus vannamei) infected with Ecytonucleospora hepatopenaei (EHP).
Fish Shellfish Immunol
January 2025
Vet Products Research & Innovation Center Co., Ltd. 141 Moo9, Thailand Science Park, Innovation Clusters (INC2) Tower D 11(th) floor, Room No. INCD1108-INCD1111 Phahonyothin Road, Khlong Nueng, Khlong Luang, Pathum Thani 12120, Thailand.
Recently, microsporidiosis caused by a microsporidian [Ecytonucleospora (Enterocytozoon) hepatopenaei, EHP] has been found to seriously impact the global shrimp industry. The aim of this study was to evaluate the therapeutic effects of fumaric acid (FA) in EHP-infected Pacific white shrimp (Penaeus vannamei). In the first 2 groups, non-EHP-infected shrimp were fed FA-supplemented (10 g/kg diet) or normal feed (CM+ and CM-, respectively).
View Article and Find Full Text PDFA widespread and ancient bacterial machinery assembles cytochrome OmcS nanowires essential for extracellular electron transfer.
Cell Chem Biol
January 2025
Microbial Sciences Institute, Yale University, West Haven, CT 06516, USA; Department of Molecular Biophysics & Biochemistry, Yale University, New Haven, CT 06511, USA. Electronic address:
Microbial extracellular electron transfer (EET) drives various globally important environmental phenomena and has biotechnology applications. Diverse prokaryotes have been proposed to perform EET via surface-displayed "nanowires" composed of multi-heme cytochromes. However, the mechanism that enables only a few cytochromes to polymerize into nanowires is unclear.
View Article and Find Full Text PDFLong-term suppression of Microcystis aeruginosa by tannic acid: Risks of microcystin pollution and proteomic mechanisms.
J Hazard Mater
January 2025
School of Environment, Jiangsu Province Engineering Research Center of Environmental Risk Prevention and Emergency Response Technology, Nanjing Normal University, Nanjing 210023, China; Jiangsu Center for Collaborative Innovation in Geographical Information Resource Development and Application, Nanjing 210023, China. Electronic address:
Harmful algal blooms are a critical eco-environmental issue with severe impacts on aquatic ecosystems and human health. Tannic acid (TA) has been suggested as an effective algal bloom control, but the molecular mechanisms of its interaction with algae cells and its effects on algal toxin release remain unclear. This study tracked toxin production and release in the toxigenic species Microcystis aeruginosa (M.
View Article and Find Full Text PDFAnchoring platinum clusters in CoP@CoNi layered double hydroxide to prepare high-performance and stable electrodes for efficient water splitting at high current density.
J Colloid Interface Sci
January 2025
Engineering Research Center of Advanced Functional Material Manufacturing of Ministry of Education, School of Chemical Engineering, Zhengzhou University, Zhengzhou, 450001 Henan, China; National Key Laboratory of Coking Coal Green Process Research, Zhengzhou University, Zhengzhou 450001, Henan, China. Electronic address:
Hydrogen production via electrocatalytic water splitting has garnered significant attention, due to the growing demand for clean and renewable energy. However, achieving low overpotential and long-term stability of water splitting catalysts at high current densities remains a major challenge. Herein, a CoP@CoNi layered double hydroxide (LDH) electrode was synthesized via a two-step electrodeposition process, demonstrating oxygen evolution reaction, with an overpotential (ƞ) of 373 mV and a Tafel slope of 64.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!